针对自身免疫抗原- fc构建物治疗黏膜天疱疮达到目的

IF 16.3 1区医学 Q1 IMMUNOLOGY

Science Immunology Pub Date : 2025-10-03 DOI:10.1126/sciimmunol.aec5745

Francesca Beretta, Valentina Damato

引用次数: 0

摘要

粘粒蛋白-3抗原- fc融合结构在寻常型天疱疮模型中显示出治疗的希望。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Taking aim at autoimmunity—Antigen-Fc constructs for mucosal pemphigus hit the mark

A desmoglein-3 antigen-Fc fusion construct shows promise as a therapeutic in a model of pemphigus vulgaris.

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来源期刊

Science Immunology Immunology and Microbiology-Immunology

CiteScore

32.90

自引率

2.00%

发文量

183

期刊介绍： Science Immunology is a peer-reviewed journal that publishes original research articles in the field of immunology. The journal encourages the submission of research findings from all areas of immunology, including studies on innate and adaptive immunity, immune cell development and differentiation, immunogenomics, systems immunology, structural immunology, antigen presentation, immunometabolism, and mucosal immunology. Additionally, the journal covers research on immune contributions to health and disease, such as host defense, inflammation, cancer immunology, autoimmunity, allergy, transplantation, and immunodeficiency. Science Immunology maintains the same high-quality standard as other journals in the Science family and aims to facilitate understanding of the immune system by showcasing innovative advances in immunology research from all organisms and model systems, including humans.