Andrey Ivanov, Konstantin Mochalov, Denis Korzhov, Milena Shestopalova, Igor Bykov, Konstantin Afanasev, Alexander Smyk, Alexander Shurygin, Andrey K. Sarychev
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Flexible metasurfaces for direct SERS identification of single extracellular vesicles
We investigate the enhancement of the electromagnetic field and the surface-enhanced Raman scattering (SERS) effect in a silver-plastic metasurface. Localized plasmon modes are excited and manifest as pronounced local maxima of the electric field, spatially confined within the dented regions of the metasurface where the silver layer exhibits minimal thickness. The spectral position of these plasmonic resonances is highly sensitive to both the silver film thickness and the non-uniformity of its distribution across the metasurface. Experimental results show good agreement with numerical simulations performed for a double-periodic metal-dielectric metasurface. The fabricated metasurface was evaluated as a SERS substrate for direct detection of individual extracellular vesicles from the Human Embryonic Kidney 293T cell line.
期刊介绍：
Optical and Quantum Electronics provides an international forum for the publication of original research papers, tutorial reviews and letters in such fields as optical physics, optical engineering and optoelectronics. Special issues are published on topics of current interest.
Optical and Quantum Electronics is published monthly. It is concerned with the technology and physics of optical systems, components and devices, i.e., with topics such as: optical fibres; semiconductor lasers and LEDs; light detection and imaging devices; nanophotonics; photonic integration and optoelectronic integrated circuits; silicon photonics; displays; optical communications from devices to systems; materials for photonics (e.g. semiconductors, glasses, graphene); the physics and simulation of optical devices and systems; nanotechnologies in photonics (including engineered nano-structures such as photonic crystals, sub-wavelength photonic structures, metamaterials, and plasmonics); advanced quantum and optoelectronic applications (e.g. quantum computing, memory and communications, quantum sensing and quantum dots); photonic sensors and bio-sensors; Terahertz phenomena; non-linear optics and ultrafast phenomena; green photonics.
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