β-地中海贫血患者红细胞输血量与发病风险的定量分析

IF 9.9 1区医学 Q1 HEMATOLOGY

American Journal of Hematology Pub Date : 2025-10-03 DOI:10.1002/ajh.70100

Khaled M Musallam,Angela Vitrano,Alessandro Inzerillo,Rosario Di Maggio,Rita Barone,Antonino Giangreco,Maria Concetta Renda,Emanuela Fecarotta,Antonio Troia,Antonino Giambona,Giovan Battista Ruffo,Efthymia Vlachaki,Theodora M Venou,Paolo Ricchi,Brunella Ziello,Marilena Serra,Elena Colizzi,Filomena Longo,Martina Culcasi,Aurelio Maggio

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引用次数: 0

摘要

在长期随访研究（de-LIGHT）中，输血负担的大小与达到目标血红蛋白阈值的输血依赖患者的发病率发展显著递增相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Quantifying Morbidity Risk Attributed to Red-Cell Transfusion Volume in Optimally Transfused Patients With β-Thalassemia.

In the long-term follow up study (de-LIGHT), the magnitude of transfusion burden was significantly and incrementally associated with morbidity development in transfusion-dependent patients achieving target hemoglobin thresholds.

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来源期刊

American Journal of Hematology 医学-血液学

CiteScore

15.70

自引率

3.90%

发文量

363

审稿时长

3-6 weeks

期刊介绍： The American Journal of Hematology offers extensive coverage of experimental and clinical aspects of blood diseases in humans and animal models. The journal publishes original contributions in both non-malignant and malignant hematological diseases, encompassing clinical and basic studies in areas such as hemostasis, thrombosis, immunology, blood banking, and stem cell biology. Clinical translational reports highlighting innovative therapeutic approaches for the diagnosis and treatment of hematological diseases are actively encouraged.The American Journal of Hematology features regular original laboratory and clinical research articles, brief research reports, critical reviews, images in hematology, as well as letters and correspondence.