Iman Abbaspour, Hoda Asefi, Abbas Soleimani, Golnaz Moradi, Samira Mirzaei
{"title":"在常规血管造影中有明显狭窄的患者与无明显狭窄的患者的非对比非ecg门控胸部CT扫描中冠状动脉钙化的患病率：一项横断面研究。","authors":"Iman Abbaspour, Hoda Asefi, Abbas Soleimani, Golnaz Moradi, Samira Mirzaei","doi":"10.1002/hsr2.71316","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background and Aims</h3>\n \n <p>Coronary artery disease is a main cause of mortality in developed and developing countries. Early diagnosis and treatment are important to reduce the burden of the disease. Correlation between coronary artery calcification in non-contrast non-ECG gated chest CT scan and conventional angiographic findings could be a helpful guide for risk assessment and the need for angiographic evaluation in patients with coronary artery calcification in non-contrast chest CT scan applied for other reasons.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>A retrospective cross-sectional study was conducted in the cardiology department of Sina hospital and patients who underwent angiographic study between march 2020 and april 2021 with recent non-contrast non ECG-gated chest CT scan were selected. patients with coronary stent and history of CABG were excluded and angiographic findings, prevalence, diameter and pattern of coronary artery calcification in CT scan was studied in the selected patients.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The prevalence of calcification in patients with significant stenosis was 94% and was significantly higher than patients without significant stenosis with prevalence of 46% (<i>p</i>-value < 0.001). Calcification length and area in patients with significant stenosis was 67.1 and 218.4 mm<sup>2</sup> and was significantly higher than patients without stenosis with length and area of 15.8 mm and 236.3 mm<sup>2</sup> (<i>p</i>-value < 0.001). there was meaningful correlation between length and area of calcification with maximum stenosis percentage seen in angiographic study (Pearson correlation: 0.61, 0.57).</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>The presence and extent of CAC on non-contrast, non-ECG-gated chest CT scans are correlated with significant coronary artery stenosis on angiography. These findings suggest that CAC assessment on routine chest CT scans can be used as a criterion for risk stratification and determining the need for angiographic evaluation to rule out significant stenosis.</p>\n </section>\n </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 10","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479365/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prevalence of Coronary Artery Calcification in Non-Contrast Non ECG-Gated Chest CT Scan of Patients With Significant Stenosis in Conventional Angiography in Comparison to Patients Without Significant Stenosis: A Cross-Sectional Study\",\"authors\":\"Iman Abbaspour, Hoda Asefi, Abbas Soleimani, Golnaz Moradi, Samira Mirzaei\",\"doi\":\"10.1002/hsr2.71316\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background and Aims</h3>\\n \\n <p>Coronary artery disease is a main cause of mortality in developed and developing countries. Early diagnosis and treatment are important to reduce the burden of the disease. Correlation between coronary artery calcification in non-contrast non-ECG gated chest CT scan and conventional angiographic findings could be a helpful guide for risk assessment and the need for angiographic evaluation in patients with coronary artery calcification in non-contrast chest CT scan applied for other reasons.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>A retrospective cross-sectional study was conducted in the cardiology department of Sina hospital and patients who underwent angiographic study between march 2020 and april 2021 with recent non-contrast non ECG-gated chest CT scan were selected. patients with coronary stent and history of CABG were excluded and angiographic findings, prevalence, diameter and pattern of coronary artery calcification in CT scan was studied in the selected patients.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>The prevalence of calcification in patients with significant stenosis was 94% and was significantly higher than patients without significant stenosis with prevalence of 46% (<i>p</i>-value < 0.001). Calcification length and area in patients with significant stenosis was 67.1 and 218.4 mm<sup>2</sup> and was significantly higher than patients without stenosis with length and area of 15.8 mm and 236.3 mm<sup>2</sup> (<i>p</i>-value < 0.001). there was meaningful correlation between length and area of calcification with maximum stenosis percentage seen in angiographic study (Pearson correlation: 0.61, 0.57).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>The presence and extent of CAC on non-contrast, non-ECG-gated chest CT scans are correlated with significant coronary artery stenosis on angiography. These findings suggest that CAC assessment on routine chest CT scans can be used as a criterion for risk stratification and determining the need for angiographic evaluation to rule out significant stenosis.</p>\\n </section>\\n </div>\",\"PeriodicalId\":36518,\"journal\":{\"name\":\"Health Science Reports\",\"volume\":\"8 10\",\"pages\":\"\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-09-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479365/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Health Science Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/hsr2.71316\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Health Science Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/hsr2.71316","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Prevalence of Coronary Artery Calcification in Non-Contrast Non ECG-Gated Chest CT Scan of Patients With Significant Stenosis in Conventional Angiography in Comparison to Patients Without Significant Stenosis: A Cross-Sectional Study
Background and Aims
Coronary artery disease is a main cause of mortality in developed and developing countries. Early diagnosis and treatment are important to reduce the burden of the disease. Correlation between coronary artery calcification in non-contrast non-ECG gated chest CT scan and conventional angiographic findings could be a helpful guide for risk assessment and the need for angiographic evaluation in patients with coronary artery calcification in non-contrast chest CT scan applied for other reasons.
Methods
A retrospective cross-sectional study was conducted in the cardiology department of Sina hospital and patients who underwent angiographic study between march 2020 and april 2021 with recent non-contrast non ECG-gated chest CT scan were selected. patients with coronary stent and history of CABG were excluded and angiographic findings, prevalence, diameter and pattern of coronary artery calcification in CT scan was studied in the selected patients.
Results
The prevalence of calcification in patients with significant stenosis was 94% and was significantly higher than patients without significant stenosis with prevalence of 46% (p-value < 0.001). Calcification length and area in patients with significant stenosis was 67.1 and 218.4 mm2 and was significantly higher than patients without stenosis with length and area of 15.8 mm and 236.3 mm2 (p-value < 0.001). there was meaningful correlation between length and area of calcification with maximum stenosis percentage seen in angiographic study (Pearson correlation: 0.61, 0.57).
Conclusion
The presence and extent of CAC on non-contrast, non-ECG-gated chest CT scans are correlated with significant coronary artery stenosis on angiography. These findings suggest that CAC assessment on routine chest CT scans can be used as a criterion for risk stratification and determining the need for angiographic evaluation to rule out significant stenosis.
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