Rosario Izquierdo-Escámez, Matteo Belletti, Irene Canal-Fontcuberta, Marta Mora-Rillo, Ester Carreño
{"title":"眼底自身荧光在念珠菌性脉络膜视网膜炎中的作用：来自一个临床病例的见解。","authors":"Rosario Izquierdo-Escámez, Matteo Belletti, Irene Canal-Fontcuberta, Marta Mora-Rillo, Ester Carreño","doi":"10.1080/09273948.2025.2560634","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To describe a case of mild Endogenous Candida Chorioretinitis (ECC) in a patient with candidemia, highlighting the value of fundus autofluorescence (FAF).</p><p><strong>Methods: </strong>A case report.</p><p><strong>Results: </strong>A 63-year-old man developed <i>Candida albicans</i> candidemia secondary to septic thrombophlebitis after abdominal surgery. Although he was visually asymptomatic, ophthalmologic evaluation revealed lesions consistent with ECC. FAF showed hyperautofluorescent lesions, including subtle foci missed on fundus exam. High-Definition Optical Coherence Tomography (HD-OCT) revealed inner retinal hyperreflectivity with mild ellipsoid zone disruption, while optical coherence tomography angiography (OCT-A) demonstrated choriocapillaris hypoperfusion partially matching the FAF findings. The lesions gradually resolved on FAF and HD-OCT during follow-up with systemic antifungal therapy, and no sequelae were observed at the 8-week follow-up.</p><p><strong>Conclusion: </strong>FAF could be incorporated into the routine evaluation of patients with candidemia. It can support diagnosis, facilitate the detection of overlooked foci, and assist in follow-up, therapeutic decision-making, and prognostic evaluation.</p>","PeriodicalId":19406,"journal":{"name":"Ocular Immunology and Inflammation","volume":" ","pages":"1-5"},"PeriodicalIF":2.0000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Role of Fundus Autofluorescence in Candida Chorioretinitis: Insights from a Clinical Case.\",\"authors\":\"Rosario Izquierdo-Escámez, Matteo Belletti, Irene Canal-Fontcuberta, Marta Mora-Rillo, Ester Carreño\",\"doi\":\"10.1080/09273948.2025.2560634\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To describe a case of mild Endogenous Candida Chorioretinitis (ECC) in a patient with candidemia, highlighting the value of fundus autofluorescence (FAF).</p><p><strong>Methods: </strong>A case report.</p><p><strong>Results: </strong>A 63-year-old man developed <i>Candida albicans</i> candidemia secondary to septic thrombophlebitis after abdominal surgery. Although he was visually asymptomatic, ophthalmologic evaluation revealed lesions consistent with ECC. FAF showed hyperautofluorescent lesions, including subtle foci missed on fundus exam. High-Definition Optical Coherence Tomography (HD-OCT) revealed inner retinal hyperreflectivity with mild ellipsoid zone disruption, while optical coherence tomography angiography (OCT-A) demonstrated choriocapillaris hypoperfusion partially matching the FAF findings. The lesions gradually resolved on FAF and HD-OCT during follow-up with systemic antifungal therapy, and no sequelae were observed at the 8-week follow-up.</p><p><strong>Conclusion: </strong>FAF could be incorporated into the routine evaluation of patients with candidemia. It can support diagnosis, facilitate the detection of overlooked foci, and assist in follow-up, therapeutic decision-making, and prognostic evaluation.</p>\",\"PeriodicalId\":19406,\"journal\":{\"name\":\"Ocular Immunology and Inflammation\",\"volume\":\" \",\"pages\":\"1-5\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ocular Immunology and Inflammation\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/09273948.2025.2560634\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ocular Immunology and Inflammation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/09273948.2025.2560634","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Role of Fundus Autofluorescence in Candida Chorioretinitis: Insights from a Clinical Case.
Purpose: To describe a case of mild Endogenous Candida Chorioretinitis (ECC) in a patient with candidemia, highlighting the value of fundus autofluorescence (FAF).
Methods: A case report.
Results: A 63-year-old man developed Candida albicans candidemia secondary to septic thrombophlebitis after abdominal surgery. Although he was visually asymptomatic, ophthalmologic evaluation revealed lesions consistent with ECC. FAF showed hyperautofluorescent lesions, including subtle foci missed on fundus exam. High-Definition Optical Coherence Tomography (HD-OCT) revealed inner retinal hyperreflectivity with mild ellipsoid zone disruption, while optical coherence tomography angiography (OCT-A) demonstrated choriocapillaris hypoperfusion partially matching the FAF findings. The lesions gradually resolved on FAF and HD-OCT during follow-up with systemic antifungal therapy, and no sequelae were observed at the 8-week follow-up.
Conclusion: FAF could be incorporated into the routine evaluation of patients with candidemia. It can support diagnosis, facilitate the detection of overlooked foci, and assist in follow-up, therapeutic decision-making, and prognostic evaluation.
期刊介绍：
Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
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