可穿戴式印刷式电容式传感器监测特应性皮炎患者

IF 4.3 2区 综合性期刊 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC
Alexandar R. Todorov;Huanghao Dai;Emily Yiu Hui Ko;Louay S. Abdulkarim;Naipapon Chupreecha;James Fuller;Emma Corden;Ying X. Teo;Russel N. Torah;Michael R. Ardern-Jones;Stephen P. Beeby
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引用次数: 0

摘要

传感器技术的最新进展通过实现对皮肤状况的持续监测和客观、数据驱动的评估,提供了改变皮肤病学的潜力。这项工作提出了一种新的可穿戴设备,用于非侵入性评估患者的特应性皮炎(AD)严重程度。该设备使用定制的交叉电容(IDC)传感器,仅对AD的生物标志物敏感,即角质层(SC)水合作用。该传感器集成在一个灵活的纺织臂带中,并与一个紧凑的读出电路配对,能够通过定制的图形用户界面(GUI)传输实时SC水化数据。该装置在不同的环境条件下具有良好的测量重复性和稳定性。对13名患者进行了测试,结果显示与标准临床评估工具(如Corneometer)有很强的相关性(r =0.595美元,p\lt 0.05美元)。电子纺织品IDC传感器识别出有症状的皮肤与没有症状的皮肤之间的差异为3-5 pF,而与Corneometer相比,差异明显较小。与目前的标准工具相比,提高的稳定性和准确性,加上适形因素和连续测量的能力,使电子纺织IDC传感器成为家庭监测AD患者的更好选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Wearable System Using Printed Interdigitated Capacitive Sensor for Monitoring Atopic Dermatitis in Patients
Recent advances in sensor technology offer the potential to transform dermatology by enabling continuous monitoring and objective, data-driven assessment of skin conditions. This work presents a novel wearable device for non-invasive assessment of atopic dermatitis (AD) severity in patients. The device uses a bespoke interdigitated capacitor (IDC) sensor, sensitive only to biomarkers of AD, namely stratum corneum (SC) hydration. The sensor is integrated into a flexible textile armband and paired with a compact readout circuit, capable of transmitting real-time SC hydration data via a custom graphical user interface (GUI). The device exhibited excellent measurement repeatability and stability under different environmental conditions. It was tested on 13 patients with the condition and demonstrated strong correlation with the standard clinical assessment tools such as the Corneometer ( $r =0.595$ , $p\lt 0.05$ ). The e-textile IDC sensor identified a difference of 3–5 pF between skin with symptoms of the condition compared to skin without, while showing significantly less variability compared to the Corneometer. The improved stability and accuracy, combined with the conformal form-factor and ability to perform continuous measurements make the e-textile IDC sensor a much better candidate for at-home monitoring of AD in patients, compared to the current standard tools.
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来源期刊
IEEE Sensors Journal
IEEE Sensors Journal 工程技术-工程:电子与电气
CiteScore
7.70
自引率
14.00%
发文量
2058
审稿时长
5.2 months
期刊介绍: The fields of interest of the IEEE Sensors Journal are the theory, design , fabrication, manufacturing and applications of devices for sensing and transducing physical, chemical and biological phenomena, with emphasis on the electronics and physics aspect of sensors and integrated sensors-actuators. IEEE Sensors Journal deals with the following: -Sensor Phenomenology, Modelling, and Evaluation -Sensor Materials, Processing, and Fabrication -Chemical and Gas Sensors -Microfluidics and Biosensors -Optical Sensors -Physical Sensors: Temperature, Mechanical, Magnetic, and others -Acoustic and Ultrasonic Sensors -Sensor Packaging -Sensor Networks -Sensor Applications -Sensor Systems: Signals, Processing, and Interfaces -Actuators and Sensor Power Systems -Sensor Signal Processing for high precision and stability (amplification, filtering, linearization, modulation/demodulation) and under harsh conditions (EMC, radiation, humidity, temperature); energy consumption/harvesting -Sensor Data Processing (soft computing with sensor data, e.g., pattern recognition, machine learning, evolutionary computation; sensor data fusion, processing of wave e.g., electromagnetic and acoustic; and non-wave, e.g., chemical, gravity, particle, thermal, radiative and non-radiative sensor data, detection, estimation and classification based on sensor data) -Sensors in Industrial Practice
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