室温下钴电催化芳香族和乙烯酰胺衍生物C-H酰基化反应

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-10-02 DOI:10.1039/d5cc04394h

Ruzal Sitdikov, Luca Meyer, Pavlo Nikolaienko, Oscar Verho

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引用次数: 0

摘要

本文报道了一种温和高效的钴催化电化学方法，利用8-氨基喹啉作为导向基团，对芳香和乙烯酰胺进行区域选择性的C-H酰基化反应。值得注意的是，该方案不需要化学计量氧化剂，并且在室温下在未分裂的细胞设置中操作，提供了具有广泛官能团耐受性的各种邻酰基化产物的可持续获取。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cobaltaelectro-Catalyzed C-H Acyloxylation of Aromatic and Vinylic Amide Derivatives at Room Temperature

Herein, we report a mild and efficient cobalt-catalyzed electrochemical method for the regioselective C-H acyloxylation of aromatic and vinylic amides, utilizing 8-aminoquinoline as the directing group. Notably, this protocol requires no stoichiometric oxidants and operates at room temperature in an undivided cell setup, providing sustainable access to a diverse range of ortho-acyloxylated products with broad functional group tolerance.

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.