在耐药癫痫患者中使用NIH工具箱认知电池：与神经心理测试的比较。

IF 2.3 3区医学 Q2 BEHAVIORAL SCIENCES

Epilepsy & Behavior Pub Date : 2025-09-29 DOI:10.1016/j.yebeh.2025.110715

Matthew J. Kreinbrink, Leila Gachechiladze , Amir Srour, Anjeli B. Inscore, Stephanie H. Chen

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引用次数: 0

摘要

认知功能是耐药性癫痫（DRE）患者治疗计划的重要考虑因素。虽然全面的神经心理学评估是评估认知功能的黄金标准，但它们是时间和资源密集型的，往往限制了它们的使用范围。美国国立卫生研究院工具箱认知电池（NIHTB-CB）提供了一个简短的，标准化的替代方案，但其在成人DRE中的效用仍未被探索。本研究通过比较30名患有DRE的成人的特定领域得分和金标准神经心理测试的得分来检验NIHTB-CB标准的效度。与语言有很强的相关性(r = 0.83, p

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Use of the NIH Toolbox Cognition Battery in patients with drug-resistant epilepsy: A comparison with neuropsychological testing

Cognitive function is an important consideration in treatment planning for patients with drug-resistant epilepsy (DRE). While comprehensive neuropsychological assessments are the gold standard for evaluating cognitive functioning, they are time and resource intensive, often restricting the scope of their use. The NIH Toolbox Cognition Battery (NIHTB-CB) offers a brief, standardized alternative, but its utility in adults with DRE remains unexplored. This study examined the criterion validity of the NIHTB-CB by comparing domain-specific scores to those from gold standard neuropsychological tests in thirty adults with DRE. Strong correlations were found for language (r = 0.83, p < 0.0001) and episodic memory (r = 0.63, p = 0.0003), while other domains showed moderate but non-significant associations. These results suggest that NIHTB-CB tests, particularly those that assess language and episodic memory, may serve as an adjunct tool to monitor and track cognitive function in DRE patients over time.

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来源期刊

Epilepsy & Behavior 医学-行为科学

CiteScore

5.40

自引率

15.40%

发文量

385

审稿时长

43 days

期刊介绍： Epilepsy & Behavior is the fastest-growing international journal uniquely devoted to the rapid dissemination of the most current information available on the behavioral aspects of seizures and epilepsy. Epilepsy & Behavior presents original peer-reviewed articles based on laboratory and clinical research. Topics are drawn from a variety of fields, including clinical neurology, neurosurgery, neuropsychiatry, neuropsychology, neurophysiology, neuropharmacology, and neuroimaging. From September 2012 Epilepsy & Behavior stopped accepting Case Reports for publication in the journal. From this date authors who submit to Epilepsy & Behavior will be offered a transfer or asked to resubmit their Case Reports to its new sister journal, Epilepsy & Behavior Case Reports.