用Schirmer泪液测试-1测定特应性皮炎犬的泪液产量。

IF 1 4区 农林科学 Q3 VETERINARY SCIENCES
Jenifer Baker, Allison Cox, Tyler Udenberg, Vincent E Defalque, Marina Leis
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引用次数: 0

摘要

目的:目的是利用Schirmer泪液测试-1 (STT-1)测量特应性皮炎犬的泪液分泌,以评估异常泪液分泌。动物:我们评估了47只被诊断为特应性皮炎的客户拥有的狗,这些狗的病史、临床症状、消除饮食试验的完成情况,以及至少满足5项Favrot诊断标准。步骤:对每只狗进行Schirmer撕裂试验。值< 15 mm/min与低泪液产生一致,提示干枯性角膜结膜炎。> ~ 25mm /min值与过度流泪引起的泪显一致。结果:47只特应性犬中有21只至少1只眼的STT-1值超出正常范围。3例STT-1值< 15 mm/min, 18例至少1眼STT-1值小于25 mm/min。结论和临床意义:这些发现提示特应性皮炎可能与泪液分泌改变有关。然而,缺乏完整的眼科评估排除了关于干枯性角膜结膜炎和外显的明确结论。验证这些观察结果的未来研究将有助于确定使用STT-1对特应性犬进行常规筛查是否有助于发现犬特应性皮炎的眼部表现,从而优化动物护理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tear production as measured by Schirmer tear test-1 in dogs with atopic dermatitis.

Objective: The objective was to measure tear production using Schirmer tear test-1 (STT-1) in dogs with atopic dermatitis, to evaluate for abnormal tear production.

Animals: We evaluated 47 client-owned dogs diagnosed with atopic dermatitis based on history, clinical signs, completion of an elimination diet trial, and fulfillment of at least 5 of Favrot's diagnostic criteria.

Procedure: Schirmer tear test-1 was conducted on each dog. Values < 15 mm/min were consistent with low tear production and suggestive of keratoconjunctivitis sicca. Values > 25 mm/min were consistent with epiphora due to excess lacrimation.

Results: Twenty-one of 47 atopic dogs had STT-1 values outside the normal range in at least 1 eye. Three had STT-1 values < 15 mm/min and 18 had STT-1 values > 25 mm/min in at least 1 eye.

Conclusion and clinical relevance: These findings suggest atopic dermatitis may be associated with altered tear production. However, the absence of a complete ophthalmic assessment precludes definitive conclusions regarding keratoconjunctivitis sicca and epiphora. Future studies to validate these observations could help determine whether routine screening of atopic dogs using the STT-1 can aid in detecting ocular manifestations of canine atopic dermatitis to optimize animal care.

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来源期刊
CiteScore
1.20
自引率
10.00%
发文量
177
审稿时长
12-24 weeks
期刊介绍: The Canadian Veterinary Journal (CVJ) provides a forum for the discussion of all matters relevant to the veterinary profession. The mission of the Journal is to educate by informing readers of progress in clinical veterinary medicine, clinical veterinary research, and related fields of endeavor. The key objective of The CVJ is to promote the art and science of veterinary medicine and the betterment of animal health. A report suggesting that animals have been unnecessarily subjected to adverse, stressful, or harsh conditions or treatments will not be processed for publication. Experimental studies using animals will only be considered for publication if the studies have been approved by an institutional animal care committee, or equivalent, and the guidelines of the Canadian Council on Animal Care, or equivalent, have been followed by the author(s).
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