{"title":"乳腺导管内乳头状瘤引起的鳞状细胞癌1例。","authors":"Kanako Nishiyama, Kumiko Okujima, Yosuke Mizuno","doi":"10.1002/ccr3.71068","DOIUrl":null,"url":null,"abstract":"<p>We present a rare case of squamous cell carcinoma arising from an intraductal papilloma in a 60-year-old female. Histopathology revealed an invasive squamous cell carcinoma with p63 positivity, coexisting with a benign papilloma. Following partial mastectomy and adjuvant therapy, the patient remained disease-free for 4 years and 8 months, highlighting the importance of early detection.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476970/pdf/","citationCount":"0","resultStr":"{\"title\":\"A Case of Squamous Cell Carcinoma Arising From an Intraductal Papilloma of the Breast\",\"authors\":\"Kanako Nishiyama, Kumiko Okujima, Yosuke Mizuno\",\"doi\":\"10.1002/ccr3.71068\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>We present a rare case of squamous cell carcinoma arising from an intraductal papilloma in a 60-year-old female. Histopathology revealed an invasive squamous cell carcinoma with p63 positivity, coexisting with a benign papilloma. Following partial mastectomy and adjuvant therapy, the patient remained disease-free for 4 years and 8 months, highlighting the importance of early detection.</p>\",\"PeriodicalId\":10327,\"journal\":{\"name\":\"Clinical Case Reports\",\"volume\":\"13 10\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-09-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476970/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.71068\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.71068","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
A Case of Squamous Cell Carcinoma Arising From an Intraductal Papilloma of the Breast
We present a rare case of squamous cell carcinoma arising from an intraductal papilloma in a 60-year-old female. Histopathology revealed an invasive squamous cell carcinoma with p63 positivity, coexisting with a benign papilloma. Following partial mastectomy and adjuvant therapy, the patient remained disease-free for 4 years and 8 months, highlighting the importance of early detection.
期刊介绍:
Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).