{"title":"一项孟加拉国改良的弯Ab针间性骨切除术（B-BANG）的中期结果：单外科医生试点研究。","authors":"Md Iftekher Iqbal, Fariah Osman","doi":"10.1155/bmri/4125584","DOIUrl":null,"url":null,"abstract":"<p><p><b>Purpose:</b> The purpose of the study is to report midterm outcomes of a pilot case series using a Bangladeshi modification of bent ab interno needle goniectomy (B-BANG) in primary open-angle glaucoma (POAG). <b>Methods:</b> This single-surgeon, nonrandomized case series included 11 eyes of 11 patients with POAG. Six eyes underwent standalone B-BANG, while five eyes underwent combined phacoemulsification with B-BANG. Preoperative and postoperative intraocular pressure (IOP), antiglaucoma medication (AGM) burden, and complications were recorded at 1, 3, and 6 months. Paired <i>t</i>-tests and Cohen's <i>d</i> effect sizes with 95% confidence intervals (CIs) were calculated. <b>Results:</b> Mean IOP reduced from 22.73 ± 7.38 to 17.00 ± 2.19 mmHg at 6 months (<i>p</i> = 0.0368; Cohen's <i>d</i> = 0.73). AGM usage decreased from 2.09 ± 0.94 to 0.45 ± 0.52 (<i>p</i> < 0.0001; <i>d</i> = 2.02). No sight-threatening complications occurred. <b>Conclusions:</b> B-BANG was feasible and reduced IOP and medication burden. Findings require confirmation in future controlled studies.</p>","PeriodicalId":9007,"journal":{"name":"BioMed Research International","volume":"2025 ","pages":"4125584"},"PeriodicalIF":2.3000,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12451078/pdf/","citationCount":"0","resultStr":"{\"title\":\"Midterm Outcomes of a Bangladeshi Modification of Bent Ab Interno Needle Goniectomy (B-BANG): Single-Surgeon Pilot Study.\",\"authors\":\"Md Iftekher Iqbal, Fariah Osman\",\"doi\":\"10.1155/bmri/4125584\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Purpose:</b> The purpose of the study is to report midterm outcomes of a pilot case series using a Bangladeshi modification of bent ab interno needle goniectomy (B-BANG) in primary open-angle glaucoma (POAG). <b>Methods:</b> This single-surgeon, nonrandomized case series included 11 eyes of 11 patients with POAG. Six eyes underwent standalone B-BANG, while five eyes underwent combined phacoemulsification with B-BANG. Preoperative and postoperative intraocular pressure (IOP), antiglaucoma medication (AGM) burden, and complications were recorded at 1, 3, and 6 months. Paired <i>t</i>-tests and Cohen's <i>d</i> effect sizes with 95% confidence intervals (CIs) were calculated. <b>Results:</b> Mean IOP reduced from 22.73 ± 7.38 to 17.00 ± 2.19 mmHg at 6 months (<i>p</i> = 0.0368; Cohen's <i>d</i> = 0.73). AGM usage decreased from 2.09 ± 0.94 to 0.45 ± 0.52 (<i>p</i> < 0.0001; <i>d</i> = 2.02). No sight-threatening complications occurred. <b>Conclusions:</b> B-BANG was feasible and reduced IOP and medication burden. Findings require confirmation in future controlled studies.</p>\",\"PeriodicalId\":9007,\"journal\":{\"name\":\"BioMed Research International\",\"volume\":\"2025 \",\"pages\":\"4125584\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-09-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12451078/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BioMed Research International\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1155/bmri/4125584\",\"RegionNum\":3,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"BIOTECHNOLOGY & APPLIED MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BioMed Research International","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1155/bmri/4125584","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
目的：本研究的目的是报告一项试点病例系列的中期结果，该病例系列使用孟加拉国改良的弯曲ab针间角骨切除术（B-BANG）治疗原发性开角型青光眼（POAG）。方法：采用单手术、非随机病例系列，包括11例POAG患者的11只眼。6只眼单独行B-BANG， 5只眼行超声乳化联合B-BANG。分别于1、3、6个月记录术前、术后眼压（IOP）、抗青光眼药物负担（AGM）及并发症。计算了配对t检验和95%置信区间（ci）的Cohen’s d效应量。结果：6个月时平均IOP由22.73±7.38 mmHg降至17.00±2.19 mmHg （p = 0.0368; Cohen’s d = 0.73）。AGM使用率由2.09±0.94降至0.45±0.52 （p < 0.0001; d = 2.02）。无视力威胁并发症发生。结论：B-BANG治疗可行，可降低眼压和药物负担。研究结果需要在未来的对照研究中得到证实。
Midterm Outcomes of a Bangladeshi Modification of Bent Ab Interno Needle Goniectomy (B-BANG): Single-Surgeon Pilot Study.
Purpose: The purpose of the study is to report midterm outcomes of a pilot case series using a Bangladeshi modification of bent ab interno needle goniectomy (B-BANG) in primary open-angle glaucoma (POAG). Methods: This single-surgeon, nonrandomized case series included 11 eyes of 11 patients with POAG. Six eyes underwent standalone B-BANG, while five eyes underwent combined phacoemulsification with B-BANG. Preoperative and postoperative intraocular pressure (IOP), antiglaucoma medication (AGM) burden, and complications were recorded at 1, 3, and 6 months. Paired t-tests and Cohen's d effect sizes with 95% confidence intervals (CIs) were calculated. Results: Mean IOP reduced from 22.73 ± 7.38 to 17.00 ± 2.19 mmHg at 6 months (p = 0.0368; Cohen's d = 0.73). AGM usage decreased from 2.09 ± 0.94 to 0.45 ± 0.52 (p < 0.0001; d = 2.02). No sight-threatening complications occurred. Conclusions: B-BANG was feasible and reduced IOP and medication burden. Findings require confirmation in future controlled studies.
期刊介绍：
BioMed Research International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies covering a wide range of subjects in life sciences and medicine. The journal is divided into 55 subject areas.
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