Emmanuel Agu, Awraris Hailu Bilchut, Esmael Habtamu, Yeshigeta Gelaw, Aemero Abateneh Mengesha, Belay Beyene, Ambahun Chernet, Ian Fetterman, Huiyu Hu, Hadley Burroughs, Renee F N Casentini, Seth Blumberg, Michael Deiner, Ariktha Srivathsan, Milan Hilde-Jones, Travis C Porco, Jessica Shantha, Scott D Nash, Benjamin F Arnold, Catherine E Oldenburg, Thomas M Lietman
{"title":"不参与医疗保健的儿童更容易患沙眼吗?","authors":"Emmanuel Agu, Awraris Hailu Bilchut, Esmael Habtamu, Yeshigeta Gelaw, Aemero Abateneh Mengesha, Belay Beyene, Ambahun Chernet, Ian Fetterman, Huiyu Hu, Hadley Burroughs, Renee F N Casentini, Seth Blumberg, Michael Deiner, Ariktha Srivathsan, Milan Hilde-Jones, Travis C Porco, Jessica Shantha, Scott D Nash, Benjamin F Arnold, Catherine E Oldenburg, Thomas M Lietman","doi":"10.4269/ajtmh.24-0582","DOIUrl":null,"url":null,"abstract":"<p><p>Distribution of azithromycin to children ages 0-9 years old is an established strategy for treating and preventing trachoma. Our study aimed to determine whether the order in which children show up for trachoma screening is correlated with their infection status. We used baseline visit data from the study Kebele Elimination of Trachoma for Ocular Health in Ethiopia. All children ages 0-9 years old in 20 randomly selected villages were tested for ocular Chlamydia trachomatis with polymerase chain reaction. We used mixed effects logistic regression to estimate the odds ratio (OR) of trachoma positivity on presentation day 1 versus later, with village as a random effect. There was no statistical difference between infection prevalence among children measured on day 1 versus those measured during the following days (OR = 0.89-fold, 95% CI: 0.65- to 1.21-fold, P = 0.44), indicating that presentation order is not a considerable factor in highly prevalent regions.</p>","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Are Children Least Engaged with Health Care More Likely to Have Trachoma?\",\"authors\":\"Emmanuel Agu, Awraris Hailu Bilchut, Esmael Habtamu, Yeshigeta Gelaw, Aemero Abateneh Mengesha, Belay Beyene, Ambahun Chernet, Ian Fetterman, Huiyu Hu, Hadley Burroughs, Renee F N Casentini, Seth Blumberg, Michael Deiner, Ariktha Srivathsan, Milan Hilde-Jones, Travis C Porco, Jessica Shantha, Scott D Nash, Benjamin F Arnold, Catherine E Oldenburg, Thomas M Lietman\",\"doi\":\"10.4269/ajtmh.24-0582\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Distribution of azithromycin to children ages 0-9 years old is an established strategy for treating and preventing trachoma. Our study aimed to determine whether the order in which children show up for trachoma screening is correlated with their infection status. We used baseline visit data from the study Kebele Elimination of Trachoma for Ocular Health in Ethiopia. All children ages 0-9 years old in 20 randomly selected villages were tested for ocular Chlamydia trachomatis with polymerase chain reaction. We used mixed effects logistic regression to estimate the odds ratio (OR) of trachoma positivity on presentation day 1 versus later, with village as a random effect. There was no statistical difference between infection prevalence among children measured on day 1 versus those measured during the following days (OR = 0.89-fold, 95% CI: 0.65- to 1.21-fold, P = 0.44), indicating that presentation order is not a considerable factor in highly prevalent regions.</p>\",\"PeriodicalId\":7752,\"journal\":{\"name\":\"American Journal of Tropical Medicine and Hygiene\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal of Tropical Medicine and Hygiene\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4269/ajtmh.24-0582\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Tropical Medicine and Hygiene","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4269/ajtmh.24-0582","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Are Children Least Engaged with Health Care More Likely to Have Trachoma?
Distribution of azithromycin to children ages 0-9 years old is an established strategy for treating and preventing trachoma. Our study aimed to determine whether the order in which children show up for trachoma screening is correlated with their infection status. We used baseline visit data from the study Kebele Elimination of Trachoma for Ocular Health in Ethiopia. All children ages 0-9 years old in 20 randomly selected villages were tested for ocular Chlamydia trachomatis with polymerase chain reaction. We used mixed effects logistic regression to estimate the odds ratio (OR) of trachoma positivity on presentation day 1 versus later, with village as a random effect. There was no statistical difference between infection prevalence among children measured on day 1 versus those measured during the following days (OR = 0.89-fold, 95% CI: 0.65- to 1.21-fold, P = 0.44), indicating that presentation order is not a considerable factor in highly prevalent regions.
期刊介绍:
The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is among the top-ranked tropical medicine journals in the world publishing original scientific articles and the latest science covering new research with an emphasis on population, clinical and laboratory science and the application of technology in the fields of tropical medicine, parasitology, immunology, infectious diseases, epidemiology, basic and molecular biology, virology and international medicine.
The Journal publishes unsolicited peer-reviewed manuscripts, review articles, short reports, images in Clinical Tropical Medicine, case studies, reports on the efficacy of new drugs and methods of treatment, prevention and control methodologies,new testing methods and equipment, book reports and Letters to the Editor. Topics range from applied epidemiology in such relevant areas as AIDS to the molecular biology of vaccine development.
The Journal is of interest to epidemiologists, parasitologists, virologists, clinicians, entomologists and public health officials who are concerned with health issues of the tropics, developing nations and emerging infectious diseases. Major granting institutions including philanthropic and governmental institutions active in the public health field, and medical and scientific libraries throughout the world purchase the Journal.
Two or more supplements to the Journal on topics of special interest are published annually. These supplements represent comprehensive and multidisciplinary discussions of issues of concern to tropical disease specialists and health issues of developing countries