{"title":"K2S2O8/ dmso介导的有机转化：综合报告。","authors":"Pragati Kushwaha, Rashi","doi":"10.1002/asia.70351","DOIUrl":null,"url":null,"abstract":"<p><p>The pursuit of sustainable and efficient methodologies for C─C and C─X bond formations, as well as other complex functionalizations, remains a fundamental goal in modern organic chemistry. In recent years, potassium persulfate (K<sub>2</sub>S<sub>2</sub>O<sub>8</sub>) and dimethyl sulfoxide (DMSO) catalytic system has attracted considerable attention owing to its environmentally benign nature, high efficiency, affordability, and mild reaction conditions. This catalytic combination has been effectively employed in a wide range of transformations, including cyclization, C─C/C─X coupling, oxygenation, and deoxygenation reactions, etc. These successes have firmly established K<sub>2</sub>S<sub>2</sub>O<sub>8</sub>/DMSO as a green, efficient, and versatile system for organic transformations. This review provides a comprehensive overview of recent developments utilizing this catalytic system, mechanistic insights, synthetic applications, and outlining future directions. With this, it aims to serve as a key resource for further development to more sustainable approaches in modern organic synthetic chemistry.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e70351"},"PeriodicalIF":3.3000,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"K<sub>2</sub>S<sub>2</sub>O<sub>8</sub>/DMSO-Mediated Organic Transformations: A Comprehensive Report.\",\"authors\":\"Pragati Kushwaha, Rashi\",\"doi\":\"10.1002/asia.70351\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The pursuit of sustainable and efficient methodologies for C─C and C─X bond formations, as well as other complex functionalizations, remains a fundamental goal in modern organic chemistry. In recent years, potassium persulfate (K<sub>2</sub>S<sub>2</sub>O<sub>8</sub>) and dimethyl sulfoxide (DMSO) catalytic system has attracted considerable attention owing to its environmentally benign nature, high efficiency, affordability, and mild reaction conditions. This catalytic combination has been effectively employed in a wide range of transformations, including cyclization, C─C/C─X coupling, oxygenation, and deoxygenation reactions, etc. These successes have firmly established K<sub>2</sub>S<sub>2</sub>O<sub>8</sub>/DMSO as a green, efficient, and versatile system for organic transformations. This review provides a comprehensive overview of recent developments utilizing this catalytic system, mechanistic insights, synthetic applications, and outlining future directions. With this, it aims to serve as a key resource for further development to more sustainable approaches in modern organic synthetic chemistry.</p>\",\"PeriodicalId\":145,\"journal\":{\"name\":\"Chemistry - An Asian Journal\",\"volume\":\" \",\"pages\":\"e70351\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2025-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemistry - An Asian Journal\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://doi.org/10.1002/asia.70351\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry - An Asian Journal","FirstCategoryId":"1","ListUrlMain":"https://doi.org/10.1002/asia.70351","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
K2S2O8/DMSO-Mediated Organic Transformations: A Comprehensive Report.
The pursuit of sustainable and efficient methodologies for C─C and C─X bond formations, as well as other complex functionalizations, remains a fundamental goal in modern organic chemistry. In recent years, potassium persulfate (K2S2O8) and dimethyl sulfoxide (DMSO) catalytic system has attracted considerable attention owing to its environmentally benign nature, high efficiency, affordability, and mild reaction conditions. This catalytic combination has been effectively employed in a wide range of transformations, including cyclization, C─C/C─X coupling, oxygenation, and deoxygenation reactions, etc. These successes have firmly established K2S2O8/DMSO as a green, efficient, and versatile system for organic transformations. This review provides a comprehensive overview of recent developments utilizing this catalytic system, mechanistic insights, synthetic applications, and outlining future directions. With this, it aims to serve as a key resource for further development to more sustainable approaches in modern organic synthetic chemistry.
期刊介绍：
Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics.
Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews.
A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal.
Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).
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