儿童期高血压史和成年期空腹血糖水平：Bogalusa研究

IF 3.7 2区医学 Q2 ENDOCRINOLOGY & METABOLISM

Journal of Diabetes Pub Date : 2025-10-01 DOI:10.1111/1753-0407.70155

Lingli Zhao, Jiahui Ouyang, Yewen Song, Hua Qu, Zhuye Gao

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引用次数: 0

摘要

背景：空腹血糖（FBG）反映心脏代谢健康，但儿童高血压（HTN）对成人FBG的长期影响尚不清楚。方法使用来自Bogalusa心脏研究的数据，我们检查了儿童HTN和成年早期FBG之间的联系，调整了种族、BMI、脉搏率和血压。结果儿童期HTN患者成年早期FBG较高（平均差值8.96 mg/dL），发生高FBG（≥126 mg/dL）的风险高4.16倍。这种效果在非裔美国人、脉搏率较高的人、超重的人或舒张压较低的人身上更为明显。结论：儿童期HTN与成年早期FBG升高有关。早期管理高血压儿童，特别是那些有代谢风险的儿童，可能有助于预防以后的糖尿病和心血管疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

History of Hypertension From Childhood and Fasting Blood Glucose Levels in Adulthood: The Bogalusa Study

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History of Hypertension From Childhood and Fasting Blood Glucose Levels in Adulthood: The Bogalusa Study

Background

Fasting blood glucose (FBG) reflects cardiometabolic health, but the long-term effects of childhood hypertension (HTN) on adult FBG are unclear.

Methods

Using data from the Bogalusa Heart Study, we examined the link between childhood HTN and FBG in early adulthood, adjusting for race, BMI, pulse rate, and blood pressure.

Results

Individuals with childhood HTN had higher FBG in early adulthood (mean difference 8.96 mg/dL) and a 4.16-fold higher risk of high FBG (≥ 126 mg/dL). The effect was stronger in African Americans, those with higher pulse rate, overweight individuals, or those with low diastolic BP.

Conclusions

Childhood HTN is linked to elevated FBG in early adulthood. Early management of hypertensive children, especially those at metabolic risk, may help prevent diabetes and cardiovascular disease later.

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来源期刊

Journal of Diabetes ENDOCRINOLOGY & METABOLISM-

CiteScore

6.50

自引率

2.20%

发文量

审稿时长

>12 weeks

期刊介绍： Journal of Diabetes (JDB) devotes itself to diabetes research, therapeutics, and education. It aims to involve researchers and practitioners in a dialogue between East and West via all aspects of epidemiology, etiology, pathogenesis, management, complications and prevention of diabetes, including the molecular, biochemical, and physiological aspects of diabetes. The Editorial team is international with a unique mix of Asian and Western participation. The Editors welcome submissions in form of original research articles, images, novel case reports and correspondence, and will solicit reviews, point-counterpoint, commentaries, editorials, news highlights, and educational content.