合成新型（奔驰）咪唑烯丙醇和咪唑1,3-二醇衍生物的高效h -还原工艺

IF 4.3 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

ACS Omega Pub Date : 2025-09-16 DOI:10.1021/acsomega.5c05122

Olfa Mhasni*, , , Naziha Châabani, , , Nahla Triaa, , , Jalloul Bouajila, , and , Farhat Rezgui,

引用次数: 0

摘要

本文报道了用NaBH4/CeCl3·7H2O对相应的（benz）咪唑酮衍生物进行区域选择性还原，合成了两个新的（benz）咪唑-烯丙醇和咪唑-1,3-二醇衍生物的高效实用方法。目标产物在温和条件下（0°C）以环氧乙烷为绿色溶剂，产率高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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An Efficient H-Reduction Protocol for the Synthesis of Novel (Benz)imidazole-allyl Alcohol and Imidazole-1,3-diol Derivatives

An efficient and practical procedure for the synthesis of two novel series of (benz)imidazole-allyl alcohol and imidazole-1,3-diol derivatives by regioselective reduction of the corresponding (benz)imidazole-ketone derivatives using NaBH₄/CeCl₃·7H₂O is herein reported. The target products were obtained in high yields under mild conditions (0 °C) and in EtOH as a green solvent.

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来源期刊

ACS Omega Chemical Engineering-General Chemical Engineering

CiteScore

6.60

自引率

4.90%

发文量

3945

审稿时长

2.4 months

期刊介绍： ACS Omega is an open-access global publication for scientific articles that describe new findings in chemistry and interfacing areas of science, without any perceived evaluation of immediate impact.