肉桂对肠道葡萄糖吸收的影响及其对2型糖尿病的治疗作用

IF 6.2 1区农林科学 Q1 AGRICULTURAL ENGINEERING

Industrial Crops and Products Pub Date : 2025-09-30 DOI:10.1016/j.indcrop.2025.122028

Hamza Assaggaf

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引用次数: 0

摘要

肉桂（Cinnamomum verum）是一种广泛应用于日常生活中的芳香植物。科学研究表明，肉桂具有降血糖的特性，可能对控制2型糖尿病患者的血糖水平非常有益。本研究利用消化功能酶α-淀粉酶和α-葡萄糖苷酶评价了肉桂水提物对肠道葡萄糖吸收的抑制作用及其体外降糖作用，并通过OECD指南中描述的方法评价了肉桂水提物对大鼠的亚急性毒性。结果表明，肉桂水提物对第二信使Na+ /葡萄糖共转运蛋白无抑制作用。因此，从电致的角度来看，肉桂对肠道葡萄糖吸收没有影响。

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Effect of Cinnamomum verum L. on intestinal glucose absorption and its use in the treatment of type 2 diabetes

Cinnamomum verum is an aromatic plant widely used in daily life. Scientific work has shown that cinnamon has hypoglycemic properties and may be very beneficial in controlling blood sugar levels in type 2 diabetes. In this work, we evaluated the inhibitory properties Cinnamomum verum aqueous extracts on intestinal glucose absorption and its antihyperglycemic effect in vitro using digestive functions enzymes, namely α-amylase and α-glucosidase, and we evaluated the subacute toxicity profiles of cinnamon extracts in rats through the approaches described in the guidelines of the OECD. The results show that the aqueous crude extract of cinnamon has no inhibitory effect on the second messenger, the Na+ /glucose cotransporter. Consequently, cinnamon has no effect on intestinal glucose absorption from an electrogenic point of view.

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来源期刊

Industrial Crops and Products 农林科学-农业工程

CiteScore

9.50

自引率

8.50%

发文量

1518

审稿时长

43 days

期刊介绍： Industrial Crops and Products is an International Journal publishing academic and industrial research on industrial (defined as non-food/non-feed) crops and products. Papers concern both crop-oriented and bio-based materials from crops-oriented research, and should be of interest to an international audience, hypothesis driven, and where comparisons are made statistics performed.