Combination of Platelet-Rich Fibrin and Carbonate Hydroxyapatite for Bone Regeneration in the Management of Radicular Cyst: A Case Report.

Introduction: Radicular cysts are the most common type of inflammatory cyst of the jaw. Management of radicular cysts may include cyst enucleation with apical resection. Spontaneous bone healing after cyst enucleation has been reported to occur in 73.5% of cases after 12 months. Residual cavity size was reduced 12.34% after 6 months, 43.46% after 12 months, and 81.30% after 24 months after surgery. This case report presents the use of platelet-rich fibrin and carbonate hydroxyapatite in the management of a radicular cyst for bone regeneration. This combination has not been previously reported. Case Report: A 31-year-old male complained of swelling of the anterior maxilla for 1.5 years. The patient had a history of pain and previous dental restorations. A biopsy confirmed the diagnosis of a radicular cyst. The cyst in the tooth region 21-23 was treated with enucleation of the cyst and apical resection. We used PRF with CHA on the cyst defect to enhance healing and bone regeneration. CBCT showed that bone density increased, and the size defect area buccal-palatal expansion reduced 54.4%, and mesial-distal expansion reduced 35.7% after 6 months of surgery. Conclusion: PRF and CHA may be used to accelerate bone regeneration in radicular cyst management.