{"title":"心灵与肠道之间的无形联系:述情障碍和疾病适应对罗马IV标准IBS患者症状严重程度的影响","authors":"Yasemin Karacan, Dilay Demirayak, Ayşe Gül Parlak","doi":"10.1111/nmo.70176","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Irritable bowel syndrome (IBS) is a gut-brain interaction disorder that significantly impacts quality of life, with symptoms influenced by stress, anxiety, dietary habits, and gut microbiota imbalances. Alexithymia, characterized by difficulties in identifying and expressing emotions, may exacerbate IBS symptoms by impairing stress management and illness perception. Additionally, poor adaptation to chronic illness can increase psychological burden and worsen symptom severity.</p><p><strong>Methods: </strong>This cross-sectional study examined 148 IBS patients diagnosed using Rome IV criteria at a gastroenterology outpatient clinic. Data were collected through validated scales, including the IBS Symptom Severity Score (IBS-SSS), Twenty-Item Toronto Alexithymia Scale (TAS-20), and Chronic Disease Adaptation Assessment Scale (CDAAS). Correlation and multiple regression analyses were conducted to identify key predictors of symptom severity.</p><p><strong>Results: </strong>IBS severity was notably high (mean IBS-SSS = 380.1 ± 61.5), with low income (B = 32.337, p = 0.002) and high alexithymia levels (B = 0.991, p = 0.045) emerging as strong predictors of increased symptom burden. Marital status also showed a notable association (B = 22.005, p = 0.085). While overall disease adaptation (CDAAS) was not directly linked to symptom severity, poor physiological adaptation correlated negatively with IBS symptoms, suggesting a critical role in disease perception. A significant inverse relationship was found between meal frequency and symptom severity (r = -0.170, p = 0.039), highlighting the impact of dietary habits on symptom control. The regression model explained 14.9% of variance (adjusted R<sup>2</sup> = 0.081).</p><p><strong>Conclusion: </strong>IBS symptom severity is partially influenced by socioeconomic status, emotional regulation, and dietary patterns. These findings underscore the need for a multidisciplinary treatment approach integrating dietary modifications, psychological interventions, and tailored patient support to enhance disease management and improve patient outcomes.</p>","PeriodicalId":19123,"journal":{"name":"Neurogastroenterology and Motility","volume":" ","pages":"e70176"},"PeriodicalIF":2.9000,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Invisible Link Between Mind and Gut: The Effect of Alexithymia and Adjustment to Illness on Symptom Severity in IBS Patients With Rome IV Criteria.\",\"authors\":\"Yasemin Karacan, Dilay Demirayak, Ayşe Gül Parlak\",\"doi\":\"10.1111/nmo.70176\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Irritable bowel syndrome (IBS) is a gut-brain interaction disorder that significantly impacts quality of life, with symptoms influenced by stress, anxiety, dietary habits, and gut microbiota imbalances. Alexithymia, characterized by difficulties in identifying and expressing emotions, may exacerbate IBS symptoms by impairing stress management and illness perception. Additionally, poor adaptation to chronic illness can increase psychological burden and worsen symptom severity.</p><p><strong>Methods: </strong>This cross-sectional study examined 148 IBS patients diagnosed using Rome IV criteria at a gastroenterology outpatient clinic. Data were collected through validated scales, including the IBS Symptom Severity Score (IBS-SSS), Twenty-Item Toronto Alexithymia Scale (TAS-20), and Chronic Disease Adaptation Assessment Scale (CDAAS). Correlation and multiple regression analyses were conducted to identify key predictors of symptom severity.</p><p><strong>Results: </strong>IBS severity was notably high (mean IBS-SSS = 380.1 ± 61.5), with low income (B = 32.337, p = 0.002) and high alexithymia levels (B = 0.991, p = 0.045) emerging as strong predictors of increased symptom burden. Marital status also showed a notable association (B = 22.005, p = 0.085). While overall disease adaptation (CDAAS) was not directly linked to symptom severity, poor physiological adaptation correlated negatively with IBS symptoms, suggesting a critical role in disease perception. A significant inverse relationship was found between meal frequency and symptom severity (r = -0.170, p = 0.039), highlighting the impact of dietary habits on symptom control. The regression model explained 14.9% of variance (adjusted R<sup>2</sup> = 0.081).</p><p><strong>Conclusion: </strong>IBS symptom severity is partially influenced by socioeconomic status, emotional regulation, and dietary patterns. These findings underscore the need for a multidisciplinary treatment approach integrating dietary modifications, psychological interventions, and tailored patient support to enhance disease management and improve patient outcomes.</p>\",\"PeriodicalId\":19123,\"journal\":{\"name\":\"Neurogastroenterology and Motility\",\"volume\":\" \",\"pages\":\"e70176\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neurogastroenterology and Motility\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/nmo.70176\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurogastroenterology and Motility","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/nmo.70176","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
背景:肠易激综合征(IBS)是一种显著影响生活质量的肠脑相互作用障碍,其症状受压力、焦虑、饮食习惯和肠道微生物群失衡的影响。以识别和表达情绪困难为特征的述情障碍可能通过损害压力管理和疾病感知而加剧肠易激综合征症状。此外,慢性疾病适应能力差会增加心理负担,加重症状严重程度。方法:本横断面研究在胃肠病学门诊检查了148例使用Rome IV标准诊断的IBS患者。通过经验证的量表收集数据,包括IBS症状严重程度评分(IBS- sss)、20项多伦多述情障碍量表(TAS-20)和慢性病适应评估量表(CDAAS)。通过相关分析和多元回归分析来确定症状严重程度的关键预测因素。结果:IBS严重程度较高(平均IBS- sss = 380.1±61.5),低收入(B = 32.337, p = 0.002)和述情障碍高水平(B = 0.991, p = 0.045)是症状负担加重的有力预测因素。婚姻状况也有显著相关性(B = 22.005, p = 0.085)。虽然总体疾病适应(CDAAS)与症状严重程度没有直接联系,但生理适应差与IBS症状呈负相关,表明在疾病感知中起关键作用。进餐频率与症状严重程度呈显著负相关(r = -0.170, p = 0.039),说明饮食习惯对症状控制的影响。回归模型解释了14.9%的方差(调整后R2 = 0.081)。结论:IBS症状严重程度受社会经济地位、情绪调节和饮食习惯的部分影响。这些发现强调了多学科治疗方法的必要性,包括饮食调整、心理干预和量身定制的患者支持,以加强疾病管理和改善患者预后。
The Invisible Link Between Mind and Gut: The Effect of Alexithymia and Adjustment to Illness on Symptom Severity in IBS Patients With Rome IV Criteria.
Background: Irritable bowel syndrome (IBS) is a gut-brain interaction disorder that significantly impacts quality of life, with symptoms influenced by stress, anxiety, dietary habits, and gut microbiota imbalances. Alexithymia, characterized by difficulties in identifying and expressing emotions, may exacerbate IBS symptoms by impairing stress management and illness perception. Additionally, poor adaptation to chronic illness can increase psychological burden and worsen symptom severity.
Methods: This cross-sectional study examined 148 IBS patients diagnosed using Rome IV criteria at a gastroenterology outpatient clinic. Data were collected through validated scales, including the IBS Symptom Severity Score (IBS-SSS), Twenty-Item Toronto Alexithymia Scale (TAS-20), and Chronic Disease Adaptation Assessment Scale (CDAAS). Correlation and multiple regression analyses were conducted to identify key predictors of symptom severity.
Results: IBS severity was notably high (mean IBS-SSS = 380.1 ± 61.5), with low income (B = 32.337, p = 0.002) and high alexithymia levels (B = 0.991, p = 0.045) emerging as strong predictors of increased symptom burden. Marital status also showed a notable association (B = 22.005, p = 0.085). While overall disease adaptation (CDAAS) was not directly linked to symptom severity, poor physiological adaptation correlated negatively with IBS symptoms, suggesting a critical role in disease perception. A significant inverse relationship was found between meal frequency and symptom severity (r = -0.170, p = 0.039), highlighting the impact of dietary habits on symptom control. The regression model explained 14.9% of variance (adjusted R2 = 0.081).
Conclusion: IBS symptom severity is partially influenced by socioeconomic status, emotional regulation, and dietary patterns. These findings underscore the need for a multidisciplinary treatment approach integrating dietary modifications, psychological interventions, and tailored patient support to enhance disease management and improve patient outcomes.
期刊介绍:
Neurogastroenterology & Motility (NMO) is the official Journal of the European Society of Neurogastroenterology & Motility (ESNM) and the American Neurogastroenterology and Motility Society (ANMS). It is edited by James Galligan, Albert Bredenoord, and Stephen Vanner. The editorial and peer review process is independent of the societies affiliated to the journal and publisher: Neither the ANMS, the ESNM or the Publisher have editorial decision-making power. Whenever these are relevant to the content being considered or published, the editors, journal management committee and editorial board declare their interests and affiliations.