胃内生性胃肠道间质瘤(GIST)是胃十二指肠肠套叠的罕见病因:1例报告并文献复习。

IF 2.3 3区 医学 Q2 PATHOLOGY
Shengwei Ji, Weijie Chen, Beiwei Zhu, Maowei Pei
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引用次数: 0

摘要

目的:报告一例罕见的成人胃十二指肠肠套叠由胃肠道间质瘤(GIST)引起,并回顾其诊断和治疗方法。方法:我们报告了一位68岁的女性胃十二指肠肠套叠继发于胃间质间质瘤,通过内窥镜和计算机断层扫描(CT)诊断。一项系统的PubMed综述确定了28例已发表的病例,分析了临床表现、影像学发现和管理策略。结果:患者最初行腹腔镜-内镜联合手术,手术不成功,需转开胃部分切除术。术中发现证实眼底肿块延伸至十二指肠,组织病理学证实为低风险GIST。所有病例均为胃源性胃肠道间质瘤。诊断评估一直依赖于CT和内窥镜检查,手术方法根据肿瘤特征而变化。结论:胃胃肠道间质瘤是成人胃十二指肠肠套叠的一种罕见但临床上重要的病因,通常需要手术治疗。多模式成像,特别是CT,在术前诊断中起着至关重要的作用,而组织病理学检查仍然是明确诊断和风险分层的必要条件。治疗应根据肿瘤大小、位置和患者因素进行个体化治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gastric endophytic gastrointestinal stromal tumor (GIST) as a rare cause of gastroduodenal intussusception: case report and literature review.

Objectives: To report a rare case of adult gastroduodenal intussusception caused by a gastric gastrointestinal stromal tumor (GIST) and review its diagnostic and therapeutic approaches.  METHODS: We present a 68-year-old female with gastroduodenal intussusception secondary to a gastric GIST, diagnosed through combined endoscopy and computed tomography (CT). A systematic PubMed review identified 28 published cases, which were analysis for clinical presentation, imaging findings, and management strategies.

Results: The patient initially underwent laparoscopic-endoscopic cooperative surgery, which was unsuccessful and required conversion to open partial gastrectomy. Intraoperative findings confirmed a fundus mass extending into the duodenum, with histopathology confirming a low-risk GIST. Among the reviewed cases, all involved GISTs of gastric origin. Diagnostic evaluation consistently relied on CT and endoscopy, with surgical approaches varying based on tumor characteristics.

Conclusions: Gastric GISTs are a rare but clinically significant cause of adult gastroduodenal intussusception, typically necessitating surgical intervention. Multimodal imaging, particularly CT, plays a crucial role in preoperative diagnosis, while histopathological examination remains essential for definitive diagnosis and risk stratification. Treatment should be individualized based on tumor size, location, and patient factors.

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来源期刊
Diagnostic Pathology
Diagnostic Pathology 医学-病理学
CiteScore
4.60
自引率
0.00%
发文量
93
审稿时长
1 months
期刊介绍: Diagnostic Pathology is an open access, peer-reviewed, online journal that considers research in surgical and clinical pathology, immunology, and biology, with a special focus on cutting-edge approaches in diagnostic pathology and tissue-based therapy. The journal covers all aspects of surgical pathology, including classic diagnostic pathology, prognosis-related diagnosis (tumor stages, prognosis markers, such as MIB-percentage, hormone receptors, etc.), and therapy-related findings. The journal also focuses on the technological aspects of pathology, including molecular biology techniques, morphometry aspects (stereology, DNA analysis, syntactic structure analysis), communication aspects (telecommunication, virtual microscopy, virtual pathology institutions, etc.), and electronic education and quality assurance (for example interactive publication, on-line references with automated updating, etc.).
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