黄芩多糖。2。黄芩多糖的结构与性质

IF 0.9 4区化学 Q4 CHEMISTRY, MEDICINAL

Chemistry of Natural Compounds Pub Date : 2025-09-17 DOI:10.1007/s10600-025-04778-0

R. K. Rakhmanberdyeva, A. A. Siddikova, Kh.M. Bobakulov, T. A. Petrova, M. Kh. Malikova, A. A. Ismailova

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引用次数: 0

摘要

通过对黄芩水溶性多糖的分离，得到了mm15 kDa的糖原糖半乳聚糖GAG-Sco。单糖残基分析表明，GAG-Sco由阿拉伯糖（35.7%）、葡萄糖（25.8%）和半乳糖（27.7%）组成。化学分析和1H和13C NMR数据发现，GAG-Sco大分子的主链由1,6结合的d -半乳糖酰基残基组成。C-2位的侧链含有葡萄糖、阿拉伯糖和寡糖片段α-Araf-(5→1)-α-Araf。水溶多糖对嗜中性粒细胞的吞噬指数有明显的影响。

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Polysaccharides from Scutellaria. II. Structure and Properties of Polysaccharides from Scutellaria comosa

The glucoarabinogalactan GAG-Sco with MM 15 kDa was obtained by fractionation of water-soluble polysaccharides from Scutellaria comosa Juz. An analysis of the monosaccharide residues showed that GAG-Sco consisted of arabinose (35.7%), glucose (25.8%), and galactose (27.7%). Chemical analyses and ¹H and ¹³C NMR spectroscopic data found that the main chain of the GAG-Sco macromolecule consisted of 1,6-bound D-galactopyranosyl residues. A side chain in the C-2 position contained glucose, arabinose, and the oligosaccharide fragment α-Araf-(5→1)-α-Araf. The water-soluble polysaccharide from S. comosa was shown to affect phagocytosis, specifically the phagocytic index of neutrophils.

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来源期刊

Chemistry of Natural Compounds 化学-有机化学

CiteScore

1.40

自引率

25.00%

发文量

265

审稿时长

7.8 months

期刊介绍： Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.