自体股静脉移植治疗真菌性胸主动脉瘤

IF 1.9 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Ningzhi Gu MD , Eimaan Shergill , D. Kirk Lawlor MD, MSc , Michael Janusz MD , Jong Moo Kim MD, MHSc , Joel Price MD, MPH , Jason Faulds MD, MHSc
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引用次数: 0

摘要

目的:真菌性胸主动脉瘤(MTAAs)是一种罕见的疾病。最常见的治疗方法是主动脉切除术、广泛清创和使用假体移植物进行在线重建。自2017年以来,我们一直使用自体股静脉(FV)修复我院所有MTAA。这是对该技术的初步描述,也是首次将自体静脉与假体进行MTAAs的比较研究。方法:本研究为单中心回顾性队列研究,纳入所有行手术修复的MTAA患者。患者被分配到FV组或假体移植物组。收集围手术期和远期结果。拟合单变量logistic回归模型来量化队列之间差异的强度。结果共纳入19例患者。前9例患者连续接受假体移植,随后10例患者接受FV移植。FV组患者术中培养阳性(90% vs 33.3%, P = 0.02),术中输血(10 vs 8单位,P = 0.08),手术时间较长(629 vs 500分钟,P = 0.07)。在FV队列中,住院死亡率(0比33%,P = 0.09)和长期死亡率(10%比55.6%,P = 0.57)均有改善的趋势。FV组患者出院回家的可能性更大(90% vs 44.4%; P = 0.05)。结论自体FV修复是一种持久、安全的治疗MTAA的方法。在我们的研究中没有住院死亡病例,也没有与静脉移植修复相关的长期并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Autogenous paneled femoral vein grafts for mycotic thoracic aortic aneurysms

Objective

Mycotic thoracic aortic aneurysms (MTAAs) are rare. The most common management has been aortic resection, wide debridement, and in-line reconstruction using prosthetic grafts. We have used autogenous femoral vein (FV) for the repair of all MTAA in our institution since 2017. This is the initial description of this technique, and the first comparative study of autogenous vein compared with prosthetic for MTAAs.

Methods

This is a single-center retrospective cohort study of all patients with MTAA who underwent operative repair. Patients were assigned to the FV or prosthetic grafts cohorts. Perioperative and long-term outcomes were collected. Univariate logistic regression models were fitted to quantify the strength of differences between the cohorts.

Results

Nineteen patients were included. The first 9 consecutive patients had prosthetic grafts, whereas the 10 subsequent patients were treated with FV grafts. Patients in the FV cohort were more likely to have positive intraoperative cultures (90% vs 33.3%; P = .02), receive intraoperative transfusions (10 vs 8 units; P = .08), and have a longer operation (629 vs 500 minutes; P = .07). There was a trend toward improved in-hospital (0 vs 33%; P = .09) and long-term mortality (10% vs 55.6%; P = .57) in the FV cohort. Patients in the FV cohort were more likely to be discharged home (90% vs 44.4%; P = .05).

Conclusions

Paneled autogenous FV repair is a durable and safe treatment for patients with MTAA. There were no in-hospital deaths in our series and there have been no long-term complications related to the vein graft repair.
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来源期刊
JTCVS Techniques
JTCVS Techniques Medicine-Surgery
CiteScore
1.60
自引率
6.20%
发文量
311
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