[结节性皮肤病]。

Uirusu Pub Date : 2025-01-01 DOI:10.2222/jsv.75.1
Mizuki Watanabe, Mitsutaka Ikezawa, Takehiro Kokuho, Kazuki Morioka
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引用次数: 0

摘要

肿块性皮肤病(LSD)是一种影响牛和水牛的病毒性疾病,由肿块性皮肤病病毒(LSDV)引起。受感染的动物通常会在全身出现大量的口结节,并伴有发烧、产奶量减少和流产等临床症状。结节状皮肤病变和坏死、脱落组织(静坐)含有高浓度的病毒,由于病毒的高度环境稳定性,是水平传播的重要来源。然而,LSDV的传播主要是由吸血的节肢动物媒介介导的,如蠓、稳定蝇和蜱。因此,病媒控制措施对于防止LSD入侵农场至关重要。减毒活疫苗是有效的,被广泛用于预防该病;然而,在许多受影响的国家,这种疾病尚未被根除。在亚洲,自2019年中国首次爆发以来,LSD继续在东南亚和东亚国家传播。在日本,第一例病例于2024年11月在福冈县的一个日化农场被确诊。虽然自今年1月以来(截至6月20日)没有报告新的病例,但邻国正在发生的疫情表明,重新引入的风险仍然很高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Lumpy Skin Disease].

Lumpy Skin Disease (LSD) is a viral disease affecting cattle and water buffaloes, caused by Lumpy Skin Disease Virus (LSDV). Infected animals typically develop numerous sikn nodules across the body, along with clinical signs such as fever, decreased milk production, and abortion. The nodular skin lesions and necrotic, detached tissues (sit-fast) contain high concentrations of the virus and, due to the virus's high environmental stability, serve as important sources of horizontal transmission. However, LSDV transmission is primarily mediated by blood-feeding arthropod vectors such as biting midges, stable flies, and ticks. Therefore, vector control measures are essential for preventing the incursion of LSD into farms. Live attenuated vaccines are effective and is widely used for the prevention of the disease; however, in many affected countries the disease has not been eradicated. In Asia, since the first outbreak in China in 2019, LSD has continued to spread in Southeast and East Asian countries. In Japan, the first case was confirmed in a daily farm in Fukuoka Prefecture in November 2024. Although no new cases have been reported since January of this year (as of June 20), ongoing outbreaks in neighboring countries indicate that the risk of reintroduction remains high.

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