髋臼周围截骨术后注射肉毒杆菌缓解疼痛的效果。

IF 1.1 4区 医学 Q3 ORTHOPEDICS
Journal of Hip Preservation Surgery Pub Date : 2025-04-14 eCollection Date: 2025-08-01 DOI:10.1093/jhps/hnaf019
Niels Bang, Bjarne Mygind-Klavsen, Bent Lund, Casper Foldager, Stig Storgaard Jacobsen
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引用次数: 0

摘要

有症状的髋关节发育不良患者可行髋臼周围截骨术(PAO),其中10%的患者术后6个月仍有疼痛。关节内利多卡因注射用于确定疼痛是否来自髋关节或髋关节周围结构的唇部病变。为了让患者有更长的时间来测试髋关节,我们想测试关节内注射肉毒杆菌毒素结合局部麻醉是否能减轻疼痛并让患者测试髋关节。11例接受PAO且术后至少6个月持续疼痛的患者关节内注射100IE肉毒杆菌素、3ml氯化钠水和3ml利多卡因。使用视觉模拟量表评分、国际髋关节结局工具(iHOT-12)和髋关节和腹股沟结局评分(HAGOS)评估注射当日和6周后的髋关节疼痛。注射髋关节肉毒杆菌素可降低疼痛程度和iHOT-12评分,注射后6周有统计学显著改善。在本研究中,在有限的患者组中,以100iu的控制剂量在3ml NaCl溶液中稀释后与利多卡因混合,髋关节注射无副作用。肉毒杆菌毒素对大多数患者的髋关节有很好的减轻疼痛的效果,与膝关节和肩关节的结果相当。本研究在有限的患者组中,以100iu, 3ml NaCl溶液混合利多卡因为控制剂量,髋关节注射无副作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pain relieving effects of Botox injection in the hip joint following a periacetabular osteotomy.

Patients with symptomatic hip dysplasia may undergo periacetabular osteotomy (PAO) and 10% of these patients have pain >6 months after the operation. An intra-articular lidocaine injection is used to determine if the pain comes from labral pathology in the hip joint or structures around the hip. To allow the patient a longer period of time to test the hip, we wanted to test if an intra-articular injection of Botox combined with local anaesthetic could reduce pain and allow the patient to test the hip. Eleven patients who received a PAO and suffered from persistent pain at least 6 months postoperative had an intra-articular joint injection with 100IE Botox, 3 ml NaCl water and 3 ml lidocaine. Hip pain on the day of injection and after 6 weeks was evaluated using the Visual Analog Scale score, International Hip Outcome Tool (iHOT-12), and Hip and Groin Outcome Score (HAGOS). Botox in the hip joint reduced the pain level and the iHOT-12 score, with a statistically significant improvement 6 weeks after injection. Hip joint injection of a controlled dosage of 100 IU diluted in 3 ml NaCl solution mixed with lidocaine had no side effects in this study with a limited group of patients. Botox has a promising pain-reducing effect on the hip joint in the majority of patients comparable with findings in knee and shoulder joints. Hip joint injection of a controlled dosage of 100 IU, 3 ml NaCl solution mixed with lidocaine had no side effects in this study with a limited group of patients.

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自引率
20.00%
发文量
45
审稿时长
12 weeks
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