Mohammad Gharib Salehi, Mohammad Hossein Golezar, Arman Sijanivandi, Sana Delavari, Maryam Yeganegi, Shadi Nouri, Nazanin Farshchian
{"title":"子宫动脉栓塞后非球形聚乙烯醇颗粒与三丙烯明胶微球的比较:回顾性研究。","authors":"Mohammad Gharib Salehi, Mohammad Hossein Golezar, Arman Sijanivandi, Sana Delavari, Maryam Yeganegi, Shadi Nouri, Nazanin Farshchian","doi":"10.25122/jml-2024-0327","DOIUrl":null,"url":null,"abstract":"<p><p>The aim of this study was to compare leiomyoma infarction rates and embolization success using pelvic MRI following uterine artery embolization (UAE) using non-spherical polyvinyl-alcohol particles (nsPVA) or tris-acryl-gelatin microspheres (TAGM). A retrospective analysis was performed in 141 patients (mean age, 38 years) who underwent standard bilateral UAE with either nsPVA (<i>n</i> = 80) or TAGM (<i>n</i> = 61). Embolization success was defined as complete infarction of all discernible fibroids. Mann-Whitney U and independent-sample <i>t</i>-test were used to compare data types. A binary logistic regression was performed. 556 fibroids were evaluated, with a median uterine volume of 435 cm<sup>3</sup> and a median dominant fibroid volume of 110 cm3. There were no significant differences between the two groups regarding baseline characteristics, including age (<i>P</i> = 0.446), uterine volume (<i>P</i> = 0.148), dominant myoma volume (<i>P</i> = 0.124), and non-infarcted myoma number (<i>P</i> = 0.092). The tumor infarction rate in the nsPVA and TAGM groups was 74% (251/337) and 79% (174/219), respectively, which was approximately similar (<i>P</i> = 0.191). Likewise, embolization success was similar among both groups (67.5% vs. 72.1% for nsPVA and TAGM, respectively, <i>P</i> = 0.589). There was an inverse relationship between the number of preliminary non-infarcted myomas and embolization success rate (<i>P</i> = 0.035). This study assessed the availability and side effects of these two substances, and patients underwent a 6-month follow-up MRI to evaluate possible consequences. According to post-embolization MRI, the leiomyoma infarction and embolization success rates for nsPVA and TAGM were similar. The decrease in uterine and myoma volumes was analogous to both drugs.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 8","pages":"766-771"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12467395/pdf/","citationCount":"0","resultStr":"{\"title\":\"Comparison between non-spherical polyvinyl alcohol particles and tris-acryl gelatin microspheres after uterine artery embolization: a retrospective study.\",\"authors\":\"Mohammad Gharib Salehi, Mohammad Hossein Golezar, Arman Sijanivandi, Sana Delavari, Maryam Yeganegi, Shadi Nouri, Nazanin Farshchian\",\"doi\":\"10.25122/jml-2024-0327\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The aim of this study was to compare leiomyoma infarction rates and embolization success using pelvic MRI following uterine artery embolization (UAE) using non-spherical polyvinyl-alcohol particles (nsPVA) or tris-acryl-gelatin microspheres (TAGM). A retrospective analysis was performed in 141 patients (mean age, 38 years) who underwent standard bilateral UAE with either nsPVA (<i>n</i> = 80) or TAGM (<i>n</i> = 61). Embolization success was defined as complete infarction of all discernible fibroids. Mann-Whitney U and independent-sample <i>t</i>-test were used to compare data types. A binary logistic regression was performed. 556 fibroids were evaluated, with a median uterine volume of 435 cm<sup>3</sup> and a median dominant fibroid volume of 110 cm3. There were no significant differences between the two groups regarding baseline characteristics, including age (<i>P</i> = 0.446), uterine volume (<i>P</i> = 0.148), dominant myoma volume (<i>P</i> = 0.124), and non-infarcted myoma number (<i>P</i> = 0.092). The tumor infarction rate in the nsPVA and TAGM groups was 74% (251/337) and 79% (174/219), respectively, which was approximately similar (<i>P</i> = 0.191). Likewise, embolization success was similar among both groups (67.5% vs. 72.1% for nsPVA and TAGM, respectively, <i>P</i> = 0.589). There was an inverse relationship between the number of preliminary non-infarcted myomas and embolization success rate (<i>P</i> = 0.035). This study assessed the availability and side effects of these two substances, and patients underwent a 6-month follow-up MRI to evaluate possible consequences. According to post-embolization MRI, the leiomyoma infarction and embolization success rates for nsPVA and TAGM were similar. 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Comparison between non-spherical polyvinyl alcohol particles and tris-acryl gelatin microspheres after uterine artery embolization: a retrospective study.
The aim of this study was to compare leiomyoma infarction rates and embolization success using pelvic MRI following uterine artery embolization (UAE) using non-spherical polyvinyl-alcohol particles (nsPVA) or tris-acryl-gelatin microspheres (TAGM). A retrospective analysis was performed in 141 patients (mean age, 38 years) who underwent standard bilateral UAE with either nsPVA (n = 80) or TAGM (n = 61). Embolization success was defined as complete infarction of all discernible fibroids. Mann-Whitney U and independent-sample t-test were used to compare data types. A binary logistic regression was performed. 556 fibroids were evaluated, with a median uterine volume of 435 cm3 and a median dominant fibroid volume of 110 cm3. There were no significant differences between the two groups regarding baseline characteristics, including age (P = 0.446), uterine volume (P = 0.148), dominant myoma volume (P = 0.124), and non-infarcted myoma number (P = 0.092). The tumor infarction rate in the nsPVA and TAGM groups was 74% (251/337) and 79% (174/219), respectively, which was approximately similar (P = 0.191). Likewise, embolization success was similar among both groups (67.5% vs. 72.1% for nsPVA and TAGM, respectively, P = 0.589). There was an inverse relationship between the number of preliminary non-infarcted myomas and embolization success rate (P = 0.035). This study assessed the availability and side effects of these two substances, and patients underwent a 6-month follow-up MRI to evaluate possible consequences. According to post-embolization MRI, the leiomyoma infarction and embolization success rates for nsPVA and TAGM were similar. The decrease in uterine and myoma volumes was analogous to both drugs.
期刊介绍:
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