Zhengyang Hao, Xiangjun Chen, Wenqian Tang, Ruipeng Wu, Bei Xue, Jingzhe Chen, Yidan Zhang, Shaokang Wang
{"title":"食品和药物同源物对胃癌作用的研究进展。","authors":"Zhengyang Hao, Xiangjun Chen, Wenqian Tang, Ruipeng Wu, Bei Xue, Jingzhe Chen, Yidan Zhang, Shaokang Wang","doi":"10.1002/cam4.71242","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Gastric cancer (GC), a common malignant tumor, poses a significant threat to human health. Conventional radiotherapy and chemotherapy regimens come with significant drawbacks, including high toxicity, adverse side effects, inadequate targeting ability, and the potential for developing drug resistance, which ultimately diminishes patients' overall well-being.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Food and medicine homology substances exhibit favorable pharmacological activity and minimal toxic side effects. They comprise a range of components that are beneficial to the human body, including high-quality proteins, vitamins, minerals, and other biologically active components such as polysaccharides, flavonoids, saponins, and alkaloids. In recent years, they have attracted considerable attention in the field of GC prevention and treatment. A comprehensive review of extant literature, alongside a rigorous analysis of contemporary nutrition and traditional Chinese medicine, forms the foundation of this study.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Its systematic approach encompasses the examination of the effects and mechanisms of food and medicine homology substances and their active ingredients on the prophylaxis and therapy of GC.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>The study's findings expand the cognitive boundaries of GC prevention and improvement and offer novel insights and directions for the development of clinical anticancer therapeutic drugs.</p>\n </section>\n </div>","PeriodicalId":139,"journal":{"name":"Cancer Medicine","volume":"14 19","pages":""},"PeriodicalIF":3.1000,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477795/pdf/","citationCount":"0","resultStr":"{\"title\":\"Research Advances of the Effects of Food and Medicine Homology Substances on Gastric Cancer\",\"authors\":\"Zhengyang Hao, Xiangjun Chen, Wenqian Tang, Ruipeng Wu, Bei Xue, Jingzhe Chen, Yidan Zhang, Shaokang Wang\",\"doi\":\"10.1002/cam4.71242\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Gastric cancer (GC), a common malignant tumor, poses a significant threat to human health. Conventional radiotherapy and chemotherapy regimens come with significant drawbacks, including high toxicity, adverse side effects, inadequate targeting ability, and the potential for developing drug resistance, which ultimately diminishes patients' overall well-being.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>Food and medicine homology substances exhibit favorable pharmacological activity and minimal toxic side effects. They comprise a range of components that are beneficial to the human body, including high-quality proteins, vitamins, minerals, and other biologically active components such as polysaccharides, flavonoids, saponins, and alkaloids. In recent years, they have attracted considerable attention in the field of GC prevention and treatment. A comprehensive review of extant literature, alongside a rigorous analysis of contemporary nutrition and traditional Chinese medicine, forms the foundation of this study.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Its systematic approach encompasses the examination of the effects and mechanisms of food and medicine homology substances and their active ingredients on the prophylaxis and therapy of GC.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>The study's findings expand the cognitive boundaries of GC prevention and improvement and offer novel insights and directions for the development of clinical anticancer therapeutic drugs.</p>\\n </section>\\n </div>\",\"PeriodicalId\":139,\"journal\":{\"name\":\"Cancer Medicine\",\"volume\":\"14 19\",\"pages\":\"\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-09-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477795/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cancer Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/cam4.71242\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer Medicine","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cam4.71242","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
Research Advances of the Effects of Food and Medicine Homology Substances on Gastric Cancer
Background
Gastric cancer (GC), a common malignant tumor, poses a significant threat to human health. Conventional radiotherapy and chemotherapy regimens come with significant drawbacks, including high toxicity, adverse side effects, inadequate targeting ability, and the potential for developing drug resistance, which ultimately diminishes patients' overall well-being.
Methods
Food and medicine homology substances exhibit favorable pharmacological activity and minimal toxic side effects. They comprise a range of components that are beneficial to the human body, including high-quality proteins, vitamins, minerals, and other biologically active components such as polysaccharides, flavonoids, saponins, and alkaloids. In recent years, they have attracted considerable attention in the field of GC prevention and treatment. A comprehensive review of extant literature, alongside a rigorous analysis of contemporary nutrition and traditional Chinese medicine, forms the foundation of this study.
Results
Its systematic approach encompasses the examination of the effects and mechanisms of food and medicine homology substances and their active ingredients on the prophylaxis and therapy of GC.
Conclusions
The study's findings expand the cognitive boundaries of GC prevention and improvement and offer novel insights and directions for the development of clinical anticancer therapeutic drugs.
期刊介绍:
Cancer Medicine is a peer-reviewed, open access, interdisciplinary journal providing rapid publication of research from global biomedical researchers across the cancer sciences. The journal will consider submissions from all oncologic specialties, including, but not limited to, the following areas:
Clinical Cancer Research
Translational research ∙ clinical trials ∙ chemotherapy ∙ radiation therapy ∙ surgical therapy ∙ clinical observations ∙ clinical guidelines ∙ genetic consultation ∙ ethical considerations
Cancer Biology:
Molecular biology ∙ cellular biology ∙ molecular genetics ∙ genomics ∙ immunology ∙ epigenetics ∙ metabolic studies ∙ proteomics ∙ cytopathology ∙ carcinogenesis ∙ drug discovery and delivery.
Cancer Prevention:
Behavioral science ∙ psychosocial studies ∙ screening ∙ nutrition ∙ epidemiology and prevention ∙ community outreach.
Bioinformatics:
Gene expressions profiles ∙ gene regulation networks ∙ genome bioinformatics ∙ pathwayanalysis ∙ prognostic biomarkers.
Cancer Medicine publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper.