氮原子插入N / N双键：直接获得三氮杂化。

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-09-29 DOI:10.1039/d5cc04472c

Prashant Kumar,Ruchir Kant,Namrata Rastogi

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引用次数: 0

摘要

本工作记录了一个氮原子插入到二氮烯部分，提供了直接进入三氮烯核心的途径。该反应采用n-氨基碘化吡啶作为单氮原子转移试剂。应用该方法合成了一种缺氧活化的三氮杂烯前药。该方法具有条件温和、操作简单、适用范围广等特点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Nitrogen atom insertion into NN double bonds: straightforward access to triazenes.

The present work documents the insertion of one nitrogen atom into a diazene moiety, providing direct access to the triazene core. N-Amino pyridinium iodide was used as the single-nitrogen-atom transfer reagent in the reaction. The strategy was applied for the synthesis of a hypoxia-activated triazene prodrug. The methodology is notable for its mild conditions, operational simplicity and wide scope.

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.