{"title":"80岁以上慢性肾病髋部骨折患者的术后并发症和30天再入院","authors":"Hua-Wen Zhang, Lu-Lu Ma, Xue-Rong Yu","doi":"10.24920/004446","DOIUrl":null,"url":null,"abstract":"<p><p><b>PURPOSE</b>: This study aimed to explore the impact of chronic kidney disease (CKD) on the prognosis of patients older than 80 years after hip fracture. <b>METHODS</b>: This retrospective, observational, single-center study included patients older than 80 years who underwent hip fracture operations between Feburary 2013 to June 2021 at our hospital. Patients were divided into two groups based on the estimated glomerular filtration rate (eGFR): the CKD group [eGFR < 60 mL/(min·1.73m<sup>2</sup>)] and the non-CKD group. Outcomes were the incidence of in-hospital postoperative infectious and non-infectious complications, 30-day readmission, and in-hospital death. Logistic regression was used to calculate the odds ratio (<i>OR</i>) of CKD on these outcomes. <b>RESULTS</b>: A total of 498 patients were included, 165 in the CKD group and 333 in the non-CKD group. Eighty-seven CKD patients experienced 140 episodes of postoperative complications. In comparison, 114 non-CKD patients had 158 episodes of postoperative complications. CKD patients were more likely to have postoperative complications than non-CKD patients (<i>OR</i> = 2.143, 95% <i>CI</i>: 1.465-3.134, <i>P</i> < 0.001). CKD increased the risk of cardiovascular complications (<i>OR =</i> 2.044, 95% <i>CI</i>: 1.245-3.356, <i>P</i> = 0.004), acute kidney injury (<i>OR</i> = 3.401, 95% <i>CI</i>: 1.905-6.072, <i>P</i> < 0.001), delirium (<i>OR</i> = 2.276, 95% <i>CI</i>: 1.140-4.543, <i>P</i> = 0.024), and gastrointestinal bleeding (<i>OR</i> = 4.151, 95% <i>CI</i>: 1.025-16.812, <i>P</i> = 0.031). The transfusion rate (<i>OR</i> = 2.457, 95% <i>CI</i>: 1.668-3.618, <i>P</i> < 0.001) and incidence of 30-day readmission (<i>OR</i> = 2.426, 95% <i>CI</i>:1.203-4.892, <i>P</i> = 0.011) in CKD patients were higher than those in patients without CKD. <b>CONCLUSION</b>: CKD is associated with poor postoperative outcomes in geriatric hip fracture patients. Special attention should be paid to patients with CKD.</p>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":" ","pages":"1-10"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Postoperative Complications and 30-day Rreadmission in Patients Older than 80 Years with Chronic Kidney Disease after Hip Fracture.\",\"authors\":\"Hua-Wen Zhang, Lu-Lu Ma, Xue-Rong Yu\",\"doi\":\"10.24920/004446\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>PURPOSE</b>: This study aimed to explore the impact of chronic kidney disease (CKD) on the prognosis of patients older than 80 years after hip fracture. <b>METHODS</b>: This retrospective, observational, single-center study included patients older than 80 years who underwent hip fracture operations between Feburary 2013 to June 2021 at our hospital. Patients were divided into two groups based on the estimated glomerular filtration rate (eGFR): the CKD group [eGFR < 60 mL/(min·1.73m<sup>2</sup>)] and the non-CKD group. Outcomes were the incidence of in-hospital postoperative infectious and non-infectious complications, 30-day readmission, and in-hospital death. Logistic regression was used to calculate the odds ratio (<i>OR</i>) of CKD on these outcomes. <b>RESULTS</b>: A total of 498 patients were included, 165 in the CKD group and 333 in the non-CKD group. Eighty-seven CKD patients experienced 140 episodes of postoperative complications. In comparison, 114 non-CKD patients had 158 episodes of postoperative complications. CKD patients were more likely to have postoperative complications than non-CKD patients (<i>OR</i> = 2.143, 95% <i>CI</i>: 1.465-3.134, <i>P</i> < 0.001). CKD increased the risk of cardiovascular complications (<i>OR =</i> 2.044, 95% <i>CI</i>: 1.245-3.356, <i>P</i> = 0.004), acute kidney injury (<i>OR</i> = 3.401, 95% <i>CI</i>: 1.905-6.072, <i>P</i> < 0.001), delirium (<i>OR</i> = 2.276, 95% <i>CI</i>: 1.140-4.543, <i>P</i> = 0.024), and gastrointestinal bleeding (<i>OR</i> = 4.151, 95% <i>CI</i>: 1.025-16.812, <i>P</i> = 0.031). The transfusion rate (<i>OR</i> = 2.457, 95% <i>CI</i>: 1.668-3.618, <i>P</i> < 0.001) and incidence of 30-day readmission (<i>OR</i> = 2.426, 95% <i>CI</i>:1.203-4.892, <i>P</i> = 0.011) in CKD patients were higher than those in patients without CKD. <b>CONCLUSION</b>: CKD is associated with poor postoperative outcomes in geriatric hip fracture patients. Special attention should be paid to patients with CKD.</p>\",\"PeriodicalId\":35615,\"journal\":{\"name\":\"Chinese Medical Sciences Journal\",\"volume\":\" \",\"pages\":\"1-10\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-09-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chinese Medical Sciences Journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.24920/004446\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Medical Sciences Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.24920/004446","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
目的:本研究旨在探讨慢性肾脏疾病(CKD)对80岁以上髋部骨折患者预后的影响。方法:这项回顾性、观察性、单中心研究纳入了2013年2月至2021年6月在我院接受髋部骨折手术的80岁以上患者。根据估计的肾小球滤过率(eGFR)将患者分为两组:CKD组[eGFR < 60 mL/(min·1.73m2)]和非CKD组。结果是院内术后感染和非感染性并发症的发生率、30天再入院和院内死亡。使用逻辑回归计算CKD对这些结果的比值比(OR)。结果:共纳入498例患者,其中CKD组165例,非CKD组333例。87例CKD患者出现140次术后并发症。相比之下,114例非ckd患者发生了158次术后并发症。CKD患者比非CKD患者更容易出现术后并发症(OR = 2.143, 95% CI: 1.465-3.134, P < 0.001)。CKD增加了心血管并发症(OR = 2.044, 95% CI: 1.245-3.356, P = 0.004)、急性肾损伤(OR = 3.401, 95% CI: 1.905-6.072, P < 0.001)、谵妄(OR = 2.276, 95% CI: 1.140-4.543, P = 0.024)和胃肠道出血(OR = 4.151, 95% CI: 1.025-16.812, P = 0.031)的风险。CKD患者输血率(OR = 2.457, 95% CI: 1.668 ~ 3.618, P < 0.001)和30天再入院率(OR = 2.426, 95% CI:1.203 ~ 4.892, P = 0.011)均高于非CKD患者。结论:CKD与老年髋部骨折患者术后不良预后相关。CKD患者应特别注意。
Postoperative Complications and 30-day Rreadmission in Patients Older than 80 Years with Chronic Kidney Disease after Hip Fracture.
PURPOSE: This study aimed to explore the impact of chronic kidney disease (CKD) on the prognosis of patients older than 80 years after hip fracture. METHODS: This retrospective, observational, single-center study included patients older than 80 years who underwent hip fracture operations between Feburary 2013 to June 2021 at our hospital. Patients were divided into two groups based on the estimated glomerular filtration rate (eGFR): the CKD group [eGFR < 60 mL/(min·1.73m2)] and the non-CKD group. Outcomes were the incidence of in-hospital postoperative infectious and non-infectious complications, 30-day readmission, and in-hospital death. Logistic regression was used to calculate the odds ratio (OR) of CKD on these outcomes. RESULTS: A total of 498 patients were included, 165 in the CKD group and 333 in the non-CKD group. Eighty-seven CKD patients experienced 140 episodes of postoperative complications. In comparison, 114 non-CKD patients had 158 episodes of postoperative complications. CKD patients were more likely to have postoperative complications than non-CKD patients (OR = 2.143, 95% CI: 1.465-3.134, P < 0.001). CKD increased the risk of cardiovascular complications (OR = 2.044, 95% CI: 1.245-3.356, P = 0.004), acute kidney injury (OR = 3.401, 95% CI: 1.905-6.072, P < 0.001), delirium (OR = 2.276, 95% CI: 1.140-4.543, P = 0.024), and gastrointestinal bleeding (OR = 4.151, 95% CI: 1.025-16.812, P = 0.031). The transfusion rate (OR = 2.457, 95% CI: 1.668-3.618, P < 0.001) and incidence of 30-day readmission (OR = 2.426, 95% CI:1.203-4.892, P = 0.011) in CKD patients were higher than those in patients without CKD. CONCLUSION: CKD is associated with poor postoperative outcomes in geriatric hip fracture patients. Special attention should be paid to patients with CKD.