隐孢子虫通过胆汁酸试验存活。

IF 6.6 1区医学 Q1 PARASITOLOGY

Trends in parasitology Pub Date : 2025-09-26 DOI:10.1016/j.pt.2025.09.006

Ryan D Pardy, Danielle Karo-Atar, Irah L King

引用次数: 0

摘要

隐孢子虫是世界范围内引起腹泻的重要病原体。然而，寄生虫的发病机制在不同种类之间和不同种类之间是不同的。Huang等人发现CpMRP1是微生物代谢物脱氧胆酸的转运体，也是决定易感小鼠感染结果的毒力因子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cryptosporidium passes the bile acid test to survive.

Cryptosporidium spp. are an important cause of diarrheal disease worldwide. However, pathogenesis can vary between and within parasite species. Huang et al. identified CpMRP1 as a transporter of the microbial metabolite deoxycholic acid and virulence factor that determines infection outcome in susceptible mice.

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来源期刊

Trends in parasitology 医学-寄生虫学

CiteScore

14.00

自引率

3.10%

发文量

148

审稿时长

6-12 weeks

期刊介绍： Since its inception as Parasitology Today in 1985, Trends in Parasitology has evolved into a highly esteemed review journal of global significance, reflecting the importance of medical and veterinary parasites worldwide. The journal serves as a hub for communication among researchers across all disciplines of parasitology, encompassing endoparasites, ectoparasites, transmission vectors, and susceptible hosts. Each monthly issue of Trends in Parasitology offers authoritative, cutting-edge, and yet accessible review articles, providing a balanced and comprehensive overview, along with opinion pieces offering personal and novel perspectives. Additionally, the journal publishes a variety of short articles designed to inform and stimulate thoughts in a lively and widely-accessible manner. These include Science & Society (discussing the interface between parasitology and the general public), Spotlight (highlighting recently published research articles), Forum (presenting single-point hypotheses), Parasite/Vector of the Month (featuring a modular display of the selected species), Letter (providing responses to recent articles in Trends in Parasitology), and Trendstalk (conducting interviews). Please note that the journal exclusively publishes literature reviews based on published data, with systematic reviews, meta-analysis, and unpublished primary research falling outside our scope.