{"title":"经口出口复位治疗Roux-En-Y胃旁路术后倾倒综合征：系统回顾和荟萃分析。","authors":"Douglas G Adler","doi":"10.1016/j.gie.2025.09.036","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and aims: </strong>Dumping syndrome (DS) is one of the significant limitations of the Roux-En-Y Gastric Bypass (RYGB) 's long-term success. Our study aimed to review the effectiveness and safety of transoral outlet reduction (TORe) for DS.</p><p><strong>Methods: </strong>From inception to May 2024, an individualized search strategy for major databases was developed. The primary and secondary outcomes of our interest were TORe's technical and clinical success rates, peri-procedural adverse events, and reintervention rates.</p><p><strong>Results: </strong>Four studies with 241 patients were included. The pooled technical success rate was 100% (CI: 99.08%-100%). The pooled mean Sigstad's score difference calculated before and after the procedure was 13.13 (CI: 11.90, 15.56, p < 0.01), reflecting clinical success. The pooled periprocedural adverse event rate was 10.46% (CI: 0.42%-28.30%), and the pooled reintervention rate was 7.99% (CI: 1.46%-18.05%).</p><p><strong>Conclusion: </strong>Our study concludes that TORe is an effective and safe procedure for treating DS among RYGB patients.</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5000,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Transoral Outlet Reduction for the Treatment of Dumping Syndrome After Roux-En-Y Gastric Bypass: A Systematic Review and Meta-Analysis.\",\"authors\":\"Douglas G Adler\",\"doi\":\"10.1016/j.gie.2025.09.036\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background and aims: </strong>Dumping syndrome (DS) is one of the significant limitations of the Roux-En-Y Gastric Bypass (RYGB) 's long-term success. Our study aimed to review the effectiveness and safety of transoral outlet reduction (TORe) for DS.</p><p><strong>Methods: </strong>From inception to May 2024, an individualized search strategy for major databases was developed. The primary and secondary outcomes of our interest were TORe's technical and clinical success rates, peri-procedural adverse events, and reintervention rates.</p><p><strong>Results: </strong>Four studies with 241 patients were included. The pooled technical success rate was 100% (CI: 99.08%-100%). The pooled mean Sigstad's score difference calculated before and after the procedure was 13.13 (CI: 11.90, 15.56, p < 0.01), reflecting clinical success. The pooled periprocedural adverse event rate was 10.46% (CI: 0.42%-28.30%), and the pooled reintervention rate was 7.99% (CI: 1.46%-18.05%).</p><p><strong>Conclusion: </strong>Our study concludes that TORe is an effective and safe procedure for treating DS among RYGB patients.</p>\",\"PeriodicalId\":12542,\"journal\":{\"name\":\"Gastrointestinal endoscopy\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":7.5000,\"publicationDate\":\"2025-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gastrointestinal endoscopy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.gie.2025.09.036\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gastrointestinal endoscopy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.gie.2025.09.036","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
Transoral Outlet Reduction for the Treatment of Dumping Syndrome After Roux-En-Y Gastric Bypass: A Systematic Review and Meta-Analysis.
Background and aims: Dumping syndrome (DS) is one of the significant limitations of the Roux-En-Y Gastric Bypass (RYGB) 's long-term success. Our study aimed to review the effectiveness and safety of transoral outlet reduction (TORe) for DS.
Methods: From inception to May 2024, an individualized search strategy for major databases was developed. The primary and secondary outcomes of our interest were TORe's technical and clinical success rates, peri-procedural adverse events, and reintervention rates.
Results: Four studies with 241 patients were included. The pooled technical success rate was 100% (CI: 99.08%-100%). The pooled mean Sigstad's score difference calculated before and after the procedure was 13.13 (CI: 11.90, 15.56, p < 0.01), reflecting clinical success. The pooled periprocedural adverse event rate was 10.46% (CI: 0.42%-28.30%), and the pooled reintervention rate was 7.99% (CI: 1.46%-18.05%).
Conclusion: Our study concludes that TORe is an effective and safe procedure for treating DS among RYGB patients.
期刊介绍：
Gastrointestinal Endoscopy is a journal publishing original, peer-reviewed articles on endoscopic procedures for studying, diagnosing, and treating digestive diseases. It covers outcomes research, prospective studies, and controlled trials of new endoscopic instruments and treatment methods. The online features include full-text articles, video and audio clips, and MEDLINE links. The journal serves as an international forum for the latest developments in the specialty, offering challenging reports from authorities worldwide. It also publishes abstracts of significant articles from other clinical publications, accompanied by expert commentaries.
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