Lulu Gu, Ni Yan, Jiajia Hu, Kangzhen Zhang, Cuili Wu, Xianghong Ye
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The Functional Independence Measure (FIM) score was recorded at admission and discharge, and the changes of each indicator were calculated. <i>T</i>-test, chi-square test, Pearson correlation analysis, and multivariate linear regression analysis were performed to explore the relationship between PhA changes and prognosis.</p><p><b>Results:</b> Compared with the PhA decrease group, patients in the PhA increase group had larger changes in FIM (20 (18, 23) vs. 13 (12, 15)), SMI (0.21 (−0.49, 0.89) kg/m<sup>2</sup> vs. −0.28 (−1.51, 0.60) kg/m<sup>2</sup>), and grip strength (3.10 (1.95, 4.30) kg vs. 0.90 (0.50, 1.20) kg) (<i>p</i> < 0.05). Multivariate regression analysis showed that PhA change was an independent influencing factor for FIM change (<i>β</i> = 0.816, <i>p</i> = 0.002) and SMI change (<i>β</i> = 0.270, <i>p</i> = 0.046). Admission PhA was negatively correlated with PhA change (<i>r</i> = −0.803, <i>p</i> < 0.001).</p><p><b>Conclusion:</b> PhA change is closely related to the daily activity ability and skeletal muscle mass of patients with intestinal failure and can be used as an objective indicator for assessing nutritional status and prognosis. Clinically, attention should be paid to the dynamic changes of patients’ PhA, and targeted nutritional support and rehabilitation measures should be adopted to improve prognosis.</p>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9424189","citationCount":"0","resultStr":"{\"title\":\"Prognostic Value of Phase Angle Changes for Functional Recovery and Nutritional Status in Patients With Intestinal Failure\",\"authors\":\"Lulu Gu, Ni Yan, Jiajia Hu, Kangzhen Zhang, Cuili Wu, Xianghong Ye\",\"doi\":\"10.1155/ijcp/9424189\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><b>Objective:</b> To investigate the relationship between phase angle (PhA) changes and daily activity ability, skeletal muscle mass, and grip strength in patients with intestinal failure.</p><p><b>Methods:</b> We enrolled 170 patients with intestinal failure, divided into a PhA increase group (<i>n</i> = 85) and a PhA decrease group (<i>n</i> = 85). General information was compared between the two groups. Bioelectrical impedance analysis was used to measure PhA, skeletal muscle mass index (SMI), and grip strength. The Functional Independence Measure (FIM) score was recorded at admission and discharge, and the changes of each indicator were calculated. <i>T</i>-test, chi-square test, Pearson correlation analysis, and multivariate linear regression analysis were performed to explore the relationship between PhA changes and prognosis.</p><p><b>Results:</b> Compared with the PhA decrease group, patients in the PhA increase group had larger changes in FIM (20 (18, 23) vs. 13 (12, 15)), SMI (0.21 (−0.49, 0.89) kg/m<sup>2</sup> vs. −0.28 (−1.51, 0.60) kg/m<sup>2</sup>), and grip strength (3.10 (1.95, 4.30) kg vs. 0.90 (0.50, 1.20) kg) (<i>p</i> < 0.05). Multivariate regression analysis showed that PhA change was an independent influencing factor for FIM change (<i>β</i> = 0.816, <i>p</i> = 0.002) and SMI change (<i>β</i> = 0.270, <i>p</i> = 0.046). Admission PhA was negatively correlated with PhA change (<i>r</i> = −0.803, <i>p</i> < 0.001).</p><p><b>Conclusion:</b> PhA change is closely related to the daily activity ability and skeletal muscle mass of patients with intestinal failure and can be used as an objective indicator for assessing nutritional status and prognosis. 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引用次数: 0
摘要
目的：探讨肠衰竭患者相位角（PhA）变化与日常活动能力、骨骼肌量、握力的关系。方法：选取170例肠衰竭患者，分为PhA升高组（n = 85）和PhA降低组（n = 85）。比较两组患者的一般信息。采用生物电阻抗分析法测量PhA、骨骼肌质量指数（SMI）和握力。分别记录两组患者入院和出院时的功能独立性评分（FIM），并计算各指标的变化情况。采用t检验、卡方检验、Pearson相关分析和多元线性回归分析，探讨PhA变化与预后的关系。结果：与PhA减少组相比，PhA增加组患者FIM (20 （18,23) vs. 13(12,15)）、SMI (0.21 （- 0.49, 0.89) kg/m2 vs. - 0.28 (- 1.51, 0.60) kg/m2）和握力(3.10 （1.95,4.30)kg vs. 0.90 (0.50, 1.20) kg）的变化更大（p < 0.05）。多因素回归分析显示，PhA变化是FIM变化（β = 0.816, p = 0.002）和SMI变化（β = 0.270, p = 0.046）的独立影响因素。入院PhA与PhA变化呈负相关（r = - 0.803, p < 0.001）。结论：PhA变化与肠衰竭患者的日常活动能力和骨骼肌质量密切相关，可作为评价肠衰竭患者营养状况和预后的客观指标。临床上应关注患者PhA的动态变化，并采取有针对性的营养支持和康复措施，改善预后。
Prognostic Value of Phase Angle Changes for Functional Recovery and Nutritional Status in Patients With Intestinal Failure
Objective: To investigate the relationship between phase angle (PhA) changes and daily activity ability, skeletal muscle mass, and grip strength in patients with intestinal failure.
Methods: We enrolled 170 patients with intestinal failure, divided into a PhA increase group (n = 85) and a PhA decrease group (n = 85). General information was compared between the two groups. Bioelectrical impedance analysis was used to measure PhA, skeletal muscle mass index (SMI), and grip strength. The Functional Independence Measure (FIM) score was recorded at admission and discharge, and the changes of each indicator were calculated. T-test, chi-square test, Pearson correlation analysis, and multivariate linear regression analysis were performed to explore the relationship between PhA changes and prognosis.
Results: Compared with the PhA decrease group, patients in the PhA increase group had larger changes in FIM (20 (18, 23) vs. 13 (12, 15)), SMI (0.21 (−0.49, 0.89) kg/m2 vs. −0.28 (−1.51, 0.60) kg/m2), and grip strength (3.10 (1.95, 4.30) kg vs. 0.90 (0.50, 1.20) kg) (p < 0.05). Multivariate regression analysis showed that PhA change was an independent influencing factor for FIM change (β = 0.816, p = 0.002) and SMI change (β = 0.270, p = 0.046). Admission PhA was negatively correlated with PhA change (r = −0.803, p < 0.001).
Conclusion: PhA change is closely related to the daily activity ability and skeletal muscle mass of patients with intestinal failure and can be used as an objective indicator for assessing nutritional status and prognosis. Clinically, attention should be paid to the dynamic changes of patients’ PhA, and targeted nutritional support and rehabilitation measures should be adopted to improve prognosis.
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