欧洲金翅雀(Carduelis Carduelis)雏鸟合并肺炎克雷伯菌和铜绿假单胞菌感染的病理观察。

IF 2.3 2区 农林科学 Q2 VETERINARY SCIENCES
Jessica Maria Abbate, Giulia D'Annunzio, Rosa Falleti, Claudio Gervasi, Valentina Ravaioli, Elisabetta Lilliu, Emma Santo, Elena Carra, Giovanni Tosi, Giovanni Lanteri
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引用次数: 0

摘要

细菌性疾病在宠物鸟中广泛存在,对雏鸟和免疫系统较弱的鸟类构成严重威胁,往往导致孵化后最初几天的高死亡率。本研究旨在描述雏鸟(Carduelis Carduelis)中肺炎克雷伯菌和铜绿假单胞菌的自然细菌共感染的病理结果,作为孵化后死亡的原因。饲养在繁殖设施中的8只雏鸟表现出无法移动、厌食症和呼吸窘迫,并在出生后1至4天死亡。大体病理表现为弥漫性肺炎伴水肿和多灶性出血,偶有肝坏死。在组织病理学上,所有检查的鸟类的主要发现包括严重、亚急性支气管肺炎和严重坏死性肝炎。支气管旁壁、肺动脉内及肝细胞坏死灶周围可见革兰氏阴性杆菌。对肺、肝和肾进行细菌学检查,分离出两株革兰氏阴性细菌。4个管家基因(即16S rRNA、rpoB、khe、ecfX)被扩增并测序,用于在物种水平上进行细菌鉴定。虽然肺炎克雷伯菌和铜绿假单胞菌是常见的革兰氏阴性病原体,并且经常在人类细菌性肺炎中共同分离,但迄今为止尚未在雏鸟中记录到这些细菌的共同感染。病原鉴定对于制定正确的病因诊断和进一步选择最合适的治疗策略至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pathological Findings of Nestling European Goldfinches (Carduelis carduelis) Co-Infected with Klebsiella pneumoniae and Pseudomonas aeruginosa.

Bacterial diseases are widespread in pet birds, posing a severe threat in nestlings and birds with weakened immune systems, often resulting in high mortality during the first days after hatching. This study aimed to describe the pathological findings of a natural bacterial co-infection with Klebsiella pneumoniae and Pseudomonas aeruginosa in nestling European goldfinches (Carduelis carduelis), as a cause of mortality after hatching. Eight nestlings kept in a breeding facility showed an inability to move, anorexia, and respiratory distress, and were found dead between 1 and 4 days of life. Gross pathological findings included diffuse pneumonia with edema and multifocal hemorrhages and occasionally hepatic necrosis. On histopathology, the main findings in all examined birds included severe, subacute bronchopneumonia and severe necrotizing hepatitis. Gram-negative bacilli were observed in parabronchial walls, within pulmonary arteries and surrounding hepatocellular necrotic foci. Lungs, livers and kidneys were sampled for bacteriological examination, resulting in two Gram-negative bacterial isolates. Four housekeeping genes (i.e., 16S rRNA; rpoB; khe; ecfX) were amplified and sequenced for bacterial identification at species level. Although K. pneumoniae and P. aeruginosa are common Gram-negative pathogens and are often co-isolated in human bacterial pneumonia, co-infection with these bacteria has not been documented in nestling goldfinches to date. Pathogen identification is essential for formulating a correct etiological diagnosis and further selecting the most appropriate therapeutic strategy.

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来源期刊
Veterinary Sciences
Veterinary Sciences VETERINARY SCIENCES-
CiteScore
2.90
自引率
8.30%
发文量
612
审稿时长
6 weeks
期刊介绍: Veterinary Sciences is an international and interdisciplinary scholarly open access journal. It publishes original that are relevant to any field of veterinary sciences, including prevention, diagnosis and treatment of disease, disorder and injury in animals. This journal covers almost all topics related to animal health and veterinary medicine. Research fields of interest include but are not limited to: anaesthesiology anatomy bacteriology biochemistry cardiology dentistry dermatology embryology endocrinology epidemiology genetics histology immunology microbiology molecular biology mycology neurobiology oncology ophthalmology parasitology pathology pharmacology physiology radiology surgery theriogenology toxicology virology.
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