Sulaiman F Aljasir, Abdelmaged A Draz, Bilal Aslam, Abdullah S M Aljohani, Madeh Sadan, Nawaf Al-Johani, Ayman Elbehiry, Waleed Al Abdulmonem, Musaad Aldubaib, Basheer Aldurubi, Abdulhakim M Alyahya, Abdulmalik Alduhami, Abdulaziz Aljaralh, Moh A Alkhamis, Jeffrey C Chandler, Bledar Bisha, Osama B Mohammed
{"title":"沙特阿拉伯AlUla地区家养-人类-野生动物界面传染病流行病学调查揭示了濒危物种重新引入的威胁。","authors":"Sulaiman F Aljasir, Abdelmaged A Draz, Bilal Aslam, Abdullah S M Aljohani, Madeh Sadan, Nawaf Al-Johani, Ayman Elbehiry, Waleed Al Abdulmonem, Musaad Aldubaib, Basheer Aldurubi, Abdulhakim M Alyahya, Abdulmalik Alduhami, Abdulaziz Aljaralh, Moh A Alkhamis, Jeffrey C Chandler, Bledar Bisha, Osama B Mohammed","doi":"10.3390/vetsci12090836","DOIUrl":null,"url":null,"abstract":"<p><p>AlUla, a unique conservation and tourism hub in Saudi Arabia, is undergoing extensive biodiversity restoration efforts, including the reintroduction of threatened wild species. However, interactions among wildlife, domestic, and synanthropic animals in these reserves raise significant concerns about disease transmission to reintroduced species. This study aimed to assess disease risks at the domestic-synanthropic-wildlife interface and identify infectious diseases posing the greatest threat to reintroduced species. A multi-phased prioritization system was developed to guide monitoring based on transmissibility to protected wildlife, susceptibility of reintroduced species, reservoir hosts, vector-borne potential, likelihood of occurrence, and disease severity. A comprehensive expert review identified 61 diseases important to the reintroduced wildlife. From this, 11 priority pathogens were selected for monitoring. A total of 7760 samples were collected from 1367 domestic and synanthropic animals and were analyzed using Real-Time PCR and/or ELISA. All priority pathogens, or prior exposure to these pathogens, were detected. Disease presence was affected by factors such as species, location, health status, and grazing habits. Taken together, these findings underscore the need for robust preventive measures to mitigate disease transmission risks and ensure the sustainability of AlUla's conservation initiatives. This study also offers a model approach to support reintroduction programs and guide future conservation efforts.</p>","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":"12 9","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12474512/pdf/","citationCount":"0","resultStr":"{\"title\":\"Epidemiological Investigation of Infectious Diseases at the Domestic-Synanthropic-Wild Animal Interface Reveals Threats to Endangered Species Reintroduction in AlUla, Saudi Arabia.\",\"authors\":\"Sulaiman F Aljasir, Abdelmaged A Draz, Bilal Aslam, Abdullah S M Aljohani, Madeh Sadan, Nawaf Al-Johani, Ayman Elbehiry, Waleed Al Abdulmonem, Musaad Aldubaib, Basheer Aldurubi, Abdulhakim M Alyahya, Abdulmalik Alduhami, Abdulaziz Aljaralh, Moh A Alkhamis, Jeffrey C Chandler, Bledar Bisha, Osama B Mohammed\",\"doi\":\"10.3390/vetsci12090836\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>AlUla, a unique conservation and tourism hub in Saudi Arabia, is undergoing extensive biodiversity restoration efforts, including the reintroduction of threatened wild species. However, interactions among wildlife, domestic, and synanthropic animals in these reserves raise significant concerns about disease transmission to reintroduced species. This study aimed to assess disease risks at the domestic-synanthropic-wildlife interface and identify infectious diseases posing the greatest threat to reintroduced species. A multi-phased prioritization system was developed to guide monitoring based on transmissibility to protected wildlife, susceptibility of reintroduced species, reservoir hosts, vector-borne potential, likelihood of occurrence, and disease severity. A comprehensive expert review identified 61 diseases important to the reintroduced wildlife. From this, 11 priority pathogens were selected for monitoring. A total of 7760 samples were collected from 1367 domestic and synanthropic animals and were analyzed using Real-Time PCR and/or ELISA. All priority pathogens, or prior exposure to these pathogens, were detected. Disease presence was affected by factors such as species, location, health status, and grazing habits. Taken together, these findings underscore the need for robust preventive measures to mitigate disease transmission risks and ensure the sustainability of AlUla's conservation initiatives. This study also offers a model approach to support reintroduction programs and guide future conservation efforts.</p>\",\"PeriodicalId\":23694,\"journal\":{\"name\":\"Veterinary Sciences\",\"volume\":\"12 9\",\"pages\":\"\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-08-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12474512/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Veterinary Sciences\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.3390/vetsci12090836\",\"RegionNum\":2,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary Sciences","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.3390/vetsci12090836","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Epidemiological Investigation of Infectious Diseases at the Domestic-Synanthropic-Wild Animal Interface Reveals Threats to Endangered Species Reintroduction in AlUla, Saudi Arabia.
AlUla, a unique conservation and tourism hub in Saudi Arabia, is undergoing extensive biodiversity restoration efforts, including the reintroduction of threatened wild species. However, interactions among wildlife, domestic, and synanthropic animals in these reserves raise significant concerns about disease transmission to reintroduced species. This study aimed to assess disease risks at the domestic-synanthropic-wildlife interface and identify infectious diseases posing the greatest threat to reintroduced species. A multi-phased prioritization system was developed to guide monitoring based on transmissibility to protected wildlife, susceptibility of reintroduced species, reservoir hosts, vector-borne potential, likelihood of occurrence, and disease severity. A comprehensive expert review identified 61 diseases important to the reintroduced wildlife. From this, 11 priority pathogens were selected for monitoring. A total of 7760 samples were collected from 1367 domestic and synanthropic animals and were analyzed using Real-Time PCR and/or ELISA. All priority pathogens, or prior exposure to these pathogens, were detected. Disease presence was affected by factors such as species, location, health status, and grazing habits. Taken together, these findings underscore the need for robust preventive measures to mitigate disease transmission risks and ensure the sustainability of AlUla's conservation initiatives. This study also offers a model approach to support reintroduction programs and guide future conservation efforts.
期刊介绍:
Veterinary Sciences is an international and interdisciplinary scholarly open access journal. It publishes original that are relevant to any field of veterinary sciences, including prevention, diagnosis and treatment of disease, disorder and injury in animals. This journal covers almost all topics related to animal health and veterinary medicine. Research fields of interest include but are not limited to: anaesthesiology anatomy bacteriology biochemistry cardiology dentistry dermatology embryology endocrinology epidemiology genetics histology immunology microbiology molecular biology mycology neurobiology oncology ophthalmology parasitology pathology pharmacology physiology radiology surgery theriogenology toxicology virology.