加那利群岛单峰骆驼体内基本元素、有机和无机污染物的综合分析:营养和环境评估的基线。

IF 2.3 2区 农林科学 Q2 VETERINARY SCIENCES
Andrea Acosta-Dacal, Adrián Melián Henríquez, Juan Alberto Corbera, Ana Macías-Montes, Manuel Zumbado, Norberto Ruiz-Suárez, José Luis Martín-Barrasa, Octavio P Luzardo, María Teresa Tejedor-Junco
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引用次数: 0

摘要

在半粗放管理下饲养的单峰骆驼可以作为环境暴露和食物链监测的哨兵,但血清参考信息仍然很少。我们的目标是提供迄今为止对加那利群岛单峰骆驼(Camelus dromedarius)生理和毒理学血清谱最全面的评估。我们纳入了114只不同性别、年龄和生殖状况的临床健康动物。使用电感耦合等离子体质谱(ICP-MS)分析血清样品中必需、有毒和潜在有毒元素。此外,采用QuEChERS萃取- UHPLC-MS/MS和GC-MS/MS相结合的高通量多残留法对农药、兽药、人用药物和持久性有机污染物等360种有机化合物进行了筛选。根据性别、年龄组和怀孕状况,基本要素在生物学上表现出一致的变化。雄性的硒和铜含量较高,而小牛的锰和锌含量较高。孕妇表现出较低的铁、锌和硒水平,与胎儿需求增加一致。这些结果为健康骆驼按生理状态分层提供了初步参考价值。相比之下,砷、汞、铅和镉等经典有毒元素的浓度非常低或检测不到。一些潜在的有毒元素,包括钡、锶和稀土元素,偶尔被检测到,但没有毒理学问题。在所有样品中仅检测到13种有机化合物(3.6%),且浓度一直很低。最常见的是多环芳烃苊(55.3%),其次是杀菌剂procymidone和多环芳烃芴。值得注意的是,在任何样品中都没有发现通常检测到的4,4'-DDE或PCB同系物的残留。这些发现证实了骆驼在低强度耕作系统下的低环境和饮食暴露,并突出了它们作为食品安全和环境监测的哨兵物种的价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comprehensive Profiling of Essential Elements and Organic and Inorganic Contaminants in Dromedary Camels from the Canary Islands: A Baseline for Nutritional and Environmental Assessment.

Dromedary camels raised under semi-extensive management can act as One Health sentinels for environmental exposures and food chain surveillance, yet serum reference information remains scarce. Our objective was to provide the most comprehensive assessment to date of physiological and toxicological serum profiles in dromedary camels (Camelus dromedarius) from the Canary Islands. We included 114 clinically healthy animals of different sex, age, and reproductive status. Serum samples were analyzed for essential, toxic, and potentially toxic elements using inductively coupled plasma mass spectrometry (ICP-MS). In addition, a high-throughput multi-residue method based on QuEChERS extraction followed by UHPLC-MS/MS and GC-MS/MS was used to screen for 360 organic compounds, including pesticides, veterinary drugs, human pharmaceuticals, and persistent organic pollutants. Essential elements showed biologically consistent variations according to sex, age group, and pregnancy status. Males had higher levels of selenium and copper, while calves showed elevated concentrations of manganese and zinc. Pregnant females exhibited lower iron, zinc, and selenium levels, consistent with increased fetal demand. These results provide preliminary reference values for healthy camels, stratified by physiological status. In contrast, classical toxic elements such as arsenic, mercury, lead, and cadmium were found at very low or undetectable concentrations. Several potentially toxic elements, including barium, strontium, and rare earth elements, were detected sporadically but without toxicological concern. Only 13 organic compounds (3.6%) were detected in any sample, and concentrations were consistently low. The most prevalent was the PAH acenaphthene (55.3%), followed by the fungicide procymidone and the PAH fluorene. Notably, no residues of the usually detected 4,4'-DDE or PCB congeners were found in any sample. These findings confirm the low environmental and dietary exposure of camels under low-intensity farming systems and highlight their value as sentinel species for food safety and environmental monitoring.

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来源期刊
Veterinary Sciences
Veterinary Sciences VETERINARY SCIENCES-
CiteScore
2.90
自引率
8.30%
发文量
612
审稿时长
6 weeks
期刊介绍: Veterinary Sciences is an international and interdisciplinary scholarly open access journal. It publishes original that are relevant to any field of veterinary sciences, including prevention, diagnosis and treatment of disease, disorder and injury in animals. This journal covers almost all topics related to animal health and veterinary medicine. Research fields of interest include but are not limited to: anaesthesiology anatomy bacteriology biochemistry cardiology dentistry dermatology embryology endocrinology epidemiology genetics histology immunology microbiology molecular biology mycology neurobiology oncology ophthalmology parasitology pathology pharmacology physiology radiology surgery theriogenology toxicology virology.
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