Numerical Study of Incidence Angle-Tuned, Guided-Mode Resonant, Metasurfaces-Based Sensors for Glucose and Blood-Related Analytes Detection.

In optical one-dimensional grating-on-layer planar structures, an optical resonance occurs when the incident light wave becomes phase-matched to a leaky waveguide mode excited in the layer underneath the grating by an appropriate tuning of the grating periodicity. Changing the refractive indices of the grating's constituents, and/or thickness, changes the resonance frequency. In the case of a two-dimensional grating atop such a smooth layer, a similar and also cavity-mode resonance can occur. This idea has straightforward usage in diverse optical sensor applications. In this study, a novel guided-mode resonance sensor design for detecting glucose and hemoglobin in minute concentrations at a wide range of incidence angles is presented. In this design, materials of the grating, such as a polymer and cesium-lead halide with a perovskite crystal structure, are examined, which will allow flexible, low-cost fabrication by soft-lithography/imprint-lithography methods. The sensitivity, figure of merit, and quality factor are reported for one- and two-dimensional grating structures. The simulations performed are based on rigorous coupled-wave analysis. Optical resonance quality factor of ∼5·105 is achieved at oblique incidence for a structure comprising a one-dimensional grating etched in a poly-vinylidene chloride layer atop a silicon nitride waveguide layer on a substrate. Record values of the above-noted characteristics are achieved with a synergetic interplay of the materials, structural dimensions, incidence angle, polarization, and grating geometry.