{"title":"D型流感病毒在意大利牛、猪、马和野猪中的传播：血清流行病学研究。","authors":"Alessandro Falsini, Chiara Coppola, Aurora Fiori, Domenico Buonavoglia, Serena Marchi, Emanuele Montomoli, Francesco Pellegrini, Gianvito Lanave, Vito Martella, Michele Camero, Claudia Maria Trombetta","doi":"10.3390/pathogens14090891","DOIUrl":null,"url":null,"abstract":"<p><p>Influenza D virus (IDV), belonging to the <i>Orthomyxoviridae</i> family, was first discovered in 2011 in pigs. Surveys in humans and animals have been carried out to decipher IDV ecology. In this seroepidemiological study, we investigated the circulation of IDV lineages across Italy in livestock and wildlife animals. A total of 1038 animal serum samples (from 246 bovines, 249 swine, 98 equines, and 445 wild boars) were tested using hemagglutination inhibition and virus neutralization assays. The results confirm bovines as the primary reservoir for IDV, with high seroprevalence for both D/660 (87%) and D/OK (80%) strains. Swine and equines demonstrated limited exposure, suggesting they are infrequent spillover hosts. Notably, wild boars showed high seroprevalence, especially for the D/660 lineage (80%), indicating their potential role in a wildlife transmission cycle. Continuous surveillance in both livestock and wildlife is essential to monitor the spread and evolution of IDV.</p>","PeriodicalId":19758,"journal":{"name":"Pathogens","volume":"14 9","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12472503/pdf/","citationCount":"0","resultStr":"{\"title\":\"Influenza D Virus Circulation Among Bovines, Swine, Equines, and Wild Boars in Italy: A Sero-Epidemiological Study.\",\"authors\":\"Alessandro Falsini, Chiara Coppola, Aurora Fiori, Domenico Buonavoglia, Serena Marchi, Emanuele Montomoli, Francesco Pellegrini, Gianvito Lanave, Vito Martella, Michele Camero, Claudia Maria Trombetta\",\"doi\":\"10.3390/pathogens14090891\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Influenza D virus (IDV), belonging to the <i>Orthomyxoviridae</i> family, was first discovered in 2011 in pigs. Surveys in humans and animals have been carried out to decipher IDV ecology. In this seroepidemiological study, we investigated the circulation of IDV lineages across Italy in livestock and wildlife animals. A total of 1038 animal serum samples (from 246 bovines, 249 swine, 98 equines, and 445 wild boars) were tested using hemagglutination inhibition and virus neutralization assays. The results confirm bovines as the primary reservoir for IDV, with high seroprevalence for both D/660 (87%) and D/OK (80%) strains. Swine and equines demonstrated limited exposure, suggesting they are infrequent spillover hosts. Notably, wild boars showed high seroprevalence, especially for the D/660 lineage (80%), indicating their potential role in a wildlife transmission cycle. Continuous surveillance in both livestock and wildlife is essential to monitor the spread and evolution of IDV.</p>\",\"PeriodicalId\":19758,\"journal\":{\"name\":\"Pathogens\",\"volume\":\"14 9\",\"pages\":\"\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2025-09-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12472503/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pathogens\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3390/pathogens14090891\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pathogens","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/pathogens14090891","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
Influenza D Virus Circulation Among Bovines, Swine, Equines, and Wild Boars in Italy: A Sero-Epidemiological Study.
Influenza D virus (IDV), belonging to the Orthomyxoviridae family, was first discovered in 2011 in pigs. Surveys in humans and animals have been carried out to decipher IDV ecology. In this seroepidemiological study, we investigated the circulation of IDV lineages across Italy in livestock and wildlife animals. A total of 1038 animal serum samples (from 246 bovines, 249 swine, 98 equines, and 445 wild boars) were tested using hemagglutination inhibition and virus neutralization assays. The results confirm bovines as the primary reservoir for IDV, with high seroprevalence for both D/660 (87%) and D/OK (80%) strains. Swine and equines demonstrated limited exposure, suggesting they are infrequent spillover hosts. Notably, wild boars showed high seroprevalence, especially for the D/660 lineage (80%), indicating their potential role in a wildlife transmission cycle. Continuous surveillance in both livestock and wildlife is essential to monitor the spread and evolution of IDV.
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Pathogens (ISSN 2076-0817) publishes reviews, regular research papers and short notes on all aspects of pathogens and pathogen-host interactions. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodical details must be provided for research articles.
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