脑静脉血栓形成：在儿科三级中心20年的经验。

IF 2.3 3区医学 Q2 HEMATOLOGY

Pediatric Blood & Cancer Pub Date : 2025-09-26 DOI:10.1002/pbc.32083

Julia Loureiro Sion, Daniele M Celeste, Bernadete L Liphaus, Marlene P Garanito, Jorge D A Carneiro

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引用次数: 0

摘要

脑静脉血栓形成（CSVT）是罕见的儿童和相关的危险因素，如脱水和感染。本研究分析了20年登记的44例小儿CSVT病例。危险因素占93%，感染是最常见的。8例患者检测到血栓形成。大多数患者（91%）接受抗凝治疗：78%接受低分子肝素治疗，20%接受未分离肝素治疗。治疗时间超过了目前的建议（中位21周），因为大多数病例是根据CHEST 2012指南进行治疗的。1例患者发生与抗凝相关的大出血。所有血栓均得到改善，49%的血栓完全消除。没有复发和死亡与抗凝有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cerebral Sinovenous Thrombosis: 20 Years of Experience in a Pediatric Tertiary Center.

Cerebral sinovenous thrombosis (CSVT) is rare in children and is related to risk factors, as dehydration and infections. This study analyzed 44 pediatric cases of CSVT from a 20-year registry. Risk factors were identified in 93%, infection being the most frequent. Thrombophilia was detected in eight patients. Most patients (91%) received anticoagulation: 78% low molecular weight heparin and 20% unfractionated heparin. Treatment duration exceeded current recommendations (median 21 weeks), as most cases were treated based on CHEST 2012 guidelines. One patient experienced major bleeding related to anticoagulation. All thrombi improved, with 49% achieving complete resolution. There were no recurrences and no fatalities linked to anticoagulation.

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来源期刊

Pediatric Blood & Cancer 医学-小儿科

CiteScore

4.90

自引率

9.40%

发文量

546

审稿时长

1.5 months

期刊介绍： Pediatric Blood & Cancer publishes the highest quality manuscripts describing basic and clinical investigations of blood disorders and malignant diseases of childhood including diagnosis, treatment, epidemiology, etiology, biology, and molecular and clinical genetics of these diseases as they affect children, adolescents, and young adults. Pediatric Blood & Cancer will also include studies on such treatment options as hematopoietic stem cell transplantation, immunology, and gene therapy.