Relationship between the triglyceride glucose index and time in range: A cross-sectional study based on patients with type 2 diabetes mellitus.

ObjectiveThe objective of this study was to investigate the relationship between the triglyceride glucose index and time in range in patients with type 2 diabetes mellitus.MethodsThis is a cross-sectional study based on patients with type 2 diabetes mellitus. The time in range was measured in all patients using continuous glucose monitoring. Differential analyses were performed to compare the differences in clinical information between groups. Linear regression and logistic regression techniques were employed to construct a novel predictive model that encompassed the triglyceride glucose index, with the aim of assessing time in range attainment. The predictive value of the new model was then assessed using receiver operator characteristic curves.ResultsLinear and logistic regression analyses showed a significant negative correlation between the triglyceride glucose index and time in range, identifying the triglyceride glucose index as an independent risk factor for time in range attainment. Furthermore, restricted cubic spline plots indicated a nonlinear correlation between the triglyceride glucose index and time in range. The area under the curve of the novel prediction model constructed on the basis of the triglyceride glucose index for predicting time in range attainment was 0.81, thus demonstrating efficacious clinical application.ConclusionsThe study revealed a nonlinear relationship between the triglyceride glucose index and time in range, highlighting the triglyceride glucose index as a crucial indicator of time in range attainment.