Gregor Prša, Tamara Serdinšek, Branka Žegura Andrić
{"title":"高等教育中心妊娠保留产物的管理:一项20年回顾性队列研究。","authors":"Gregor Prša, Tamara Serdinšek, Branka Žegura Andrić","doi":"10.1186/s12905-025-03995-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Retained products of conception (RPOC) are defined as the persistence of trophoblastic tissue or placenta inside the uterine cavity after pregnancy. Management is challenging because there are no clearly defined diagnostic criteria, evidence-based guidelines, or treatment protocols. Our aim was to determine the success and complication rate of different methods of RPOC management at our tertiary centre in the last 20 years.</p><p><strong>Methods: </strong>We retrospectively collected data from patients with RPOC treated in our Clinic from 2003 to 2021 in three-year intervals. The following data were obtained: age, type of RPOC, type of treatment, complications, histopathological evaluation of the acquired tissue, and the need for transfusion.</p><p><strong>Conclusions: </strong>Our study shows that hysteroscopy and D&C are highly successful methods of RPOC, however, the complication rate in D&C is significantly higher. Moreover, less invasive treatment of RPOC using expectant and medical approach is plausible, especially in asymptomatic patients.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"440"},"PeriodicalIF":2.7000,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12466049/pdf/","citationCount":"0","resultStr":"{\"title\":\"Management of retained products of conception in a tertiary centre: a 20-year retrospective cohort study.\",\"authors\":\"Gregor Prša, Tamara Serdinšek, Branka Žegura Andrić\",\"doi\":\"10.1186/s12905-025-03995-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Retained products of conception (RPOC) are defined as the persistence of trophoblastic tissue or placenta inside the uterine cavity after pregnancy. Management is challenging because there are no clearly defined diagnostic criteria, evidence-based guidelines, or treatment protocols. Our aim was to determine the success and complication rate of different methods of RPOC management at our tertiary centre in the last 20 years.</p><p><strong>Methods: </strong>We retrospectively collected data from patients with RPOC treated in our Clinic from 2003 to 2021 in three-year intervals. The following data were obtained: age, type of RPOC, type of treatment, complications, histopathological evaluation of the acquired tissue, and the need for transfusion.</p><p><strong>Conclusions: </strong>Our study shows that hysteroscopy and D&C are highly successful methods of RPOC, however, the complication rate in D&C is significantly higher. Moreover, less invasive treatment of RPOC using expectant and medical approach is plausible, especially in asymptomatic patients.</p>\",\"PeriodicalId\":9204,\"journal\":{\"name\":\"BMC Women's Health\",\"volume\":\"25 1\",\"pages\":\"440\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2025-09-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12466049/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Women's Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12905-025-03995-7\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Women's Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12905-025-03995-7","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
背景:受孕保留产物(Retained products of conception, RPOC)被定义为妊娠后子宫腔内滋养层组织或胎盘的残留。管理是具有挑战性的,因为没有明确定义的诊断标准,循证指南或治疗方案。我们的目的是确定不同方法的RPOC管理在过去20年在我们的第三中心的成功率和并发症率。方法:我们回顾性收集2003年至2021年在我们诊所治疗的RPOC患者的资料,每三年一次。获得以下数据:年龄、RPOC类型、治疗类型、并发症、获得性组织的组织病理学评估以及是否需要输血。结论:我们的研究表明宫腔镜和D&C是治疗RPOC非常成功的方法,但D&C的并发症发生率明显较高。此外,采用期待和医学方法对RPOC进行微创治疗是可行的,特别是在无症状患者中。
Management of retained products of conception in a tertiary centre: a 20-year retrospective cohort study.
Background: Retained products of conception (RPOC) are defined as the persistence of trophoblastic tissue or placenta inside the uterine cavity after pregnancy. Management is challenging because there are no clearly defined diagnostic criteria, evidence-based guidelines, or treatment protocols. Our aim was to determine the success and complication rate of different methods of RPOC management at our tertiary centre in the last 20 years.
Methods: We retrospectively collected data from patients with RPOC treated in our Clinic from 2003 to 2021 in three-year intervals. The following data were obtained: age, type of RPOC, type of treatment, complications, histopathological evaluation of the acquired tissue, and the need for transfusion.
Conclusions: Our study shows that hysteroscopy and D&C are highly successful methods of RPOC, however, the complication rate in D&C is significantly higher. Moreover, less invasive treatment of RPOC using expectant and medical approach is plausible, especially in asymptomatic patients.
期刊介绍:
BMC Women''s Health is an open access, peer-reviewed journal that considers articles on all aspects of the health and wellbeing of adolescent girls and women, with a particular focus on the physical, mental, and emotional health of women in developed and developing nations. The journal welcomes submissions on women''s public health issues, health behaviours, breast cancer, gynecological diseases, mental health and health promotion.