A. P. Filippov, S. V. Rodchenko, T. Yu. Kirila, N. D. Kozina, A. V. Tenkovtsev
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Behavior of Complexes of Poly-2-alkyl-5,6-dihydrooxazine Block Copolymers with Curcumin in Aqueous Solutions
Complexes of block copolymers of poly-2-ethyl-5,6-dihydrooxazine and poly-2-isopropyl-5,6-dihydrooxazine with curcumin have been prepared. The binding constants were determined, the high values of which indicate a strong binding of curcumin to the block copolymers. Self-organization in aqueous solutions of the obtained complexes was studied by light scattering and turbidimetry. It has been shown that on heating one phase transition was observed in the complex solutions. Concentration dependences of the phase separation temperature have been determined. It has been established that the phase separation temperature increases by 2–4°C on passage from block copolymer solutions to solutions of the complexes.
期刊介绍:
Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.