花椒果皮中分离的化合物及其抑菌活性研究

IF 0.9 4区化学 Q4 CHEMISTRY, MEDICINAL

Chemistry of Natural Compounds Pub Date : 2025-07-25 DOI:10.1007/s10600-025-04745-9

Jing-Zhi Zhao, Xiao-Juan Huang, Khalid Hassan Mohamed, Bang-Yin Tan, Wei-Yan Hu, Rong-Ping Zhang, Hao-Fei Yu, Ying Guo, Lan-Chun Zhang

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引用次数: 0

摘要

从花椒果皮中分离出一种未见报道的无环单萜，zanthungeanumol A(1)和11种已知的生物碱2-12。活性评价表明，化合物7对金黄色葡萄球菌具有较强的抑菌活性，化合物8对大肠杆菌140具有较强的抑菌活性，MIC值为6.25 μg/mL，其抑菌活性与植物源性抗菌药物小檗碱相当。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Compounds Isolated from the Pericarp of Zanthoxylum bungeanum and Their Antibacterial Activity

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Compounds Isolated from the Pericarp of Zanthoxylum bungeanum and Their Antibacterial Activity

A previously unreported acyclic monoterpene, zanthungeanumol A (1), and eleven known alkaloids 2–12 were isolated from the pericarps of Zanthoxylum bungeanum. The activity evaluation showed that compound 7 exhibited potent antibacterial activities against Staphylococcus aureus, while compound 8 exhibited significant antimicrobial activity against Escherichia coli 140 with a MIC value of 6.25 μg/mL, and their activities were comparable to the plant-derived antibacterial drug berberine.

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来源期刊

Chemistry of Natural Compounds 化学-有机化学

CiteScore

1.40

自引率

25.00%

发文量

265

审稿时长

7.8 months

期刊介绍： Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.