{"title":"磺化三聚氰胺甲醛树脂在Biginelli反应中的催化作用：3,4 -二氢嘧啶酮的合成","authors":"Dariush Khalili, Fatemeh Rezaei","doi":"10.1007/s40995-025-01795-0","DOIUrl":null,"url":null,"abstract":"<div><p>In this study, we examined the potential ability of the sulfonated melamine–formaldehyde resin (SMFR) as an acidic heterogeneous catalyst in the multicomponent synthesis of 3, 4-dihydropyrimidine. The incorporation of sulfonic acid groups into the melamine–formaldehyde resin framework resulted in a highly active and recyclable catalyst, promoting reactions under mild and environmentally friendly conditions. Key advantages of this method include short reaction times, high product yields, and efficient catalysis with minimal catalyst loading. The synthesized compounds were structurally confirmed through FT-IR, <sup>13</sup>C NMR, and <sup>1</sup>H NMR spectroscopy, demonstrating the efficiency and reliability of the catalytic system under green synthesis conditions.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":600,"journal":{"name":"Iranian Journal of Science and Technology, Transactions A: Science","volume":"49 4","pages":"943 - 952"},"PeriodicalIF":1.4000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sulfonated Melamine–Formaldehyde Resin as a Robust Catalyst for Biginelli Reactions: Synthesis of 3, 4-Dihydropyrimidinones\",\"authors\":\"Dariush Khalili, Fatemeh Rezaei\",\"doi\":\"10.1007/s40995-025-01795-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In this study, we examined the potential ability of the sulfonated melamine–formaldehyde resin (SMFR) as an acidic heterogeneous catalyst in the multicomponent synthesis of 3, 4-dihydropyrimidine. The incorporation of sulfonic acid groups into the melamine–formaldehyde resin framework resulted in a highly active and recyclable catalyst, promoting reactions under mild and environmentally friendly conditions. Key advantages of this method include short reaction times, high product yields, and efficient catalysis with minimal catalyst loading. The synthesized compounds were structurally confirmed through FT-IR, <sup>13</sup>C NMR, and <sup>1</sup>H NMR spectroscopy, demonstrating the efficiency and reliability of the catalytic system under green synthesis conditions.</p><h3>Graphical Abstract</h3>\\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":600,\"journal\":{\"name\":\"Iranian Journal of Science and Technology, Transactions A: Science\",\"volume\":\"49 4\",\"pages\":\"943 - 952\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-03-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Iranian Journal of Science and Technology, Transactions A: Science\",\"FirstCategoryId\":\"4\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s40995-025-01795-0\",\"RegionNum\":4,\"RegionCategory\":\"综合性期刊\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MULTIDISCIPLINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Iranian Journal of Science and Technology, Transactions A: Science","FirstCategoryId":"4","ListUrlMain":"https://link.springer.com/article/10.1007/s40995-025-01795-0","RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
Sulfonated Melamine–Formaldehyde Resin as a Robust Catalyst for Biginelli Reactions: Synthesis of 3, 4-Dihydropyrimidinones
In this study, we examined the potential ability of the sulfonated melamine–formaldehyde resin (SMFR) as an acidic heterogeneous catalyst in the multicomponent synthesis of 3, 4-dihydropyrimidine. The incorporation of sulfonic acid groups into the melamine–formaldehyde resin framework resulted in a highly active and recyclable catalyst, promoting reactions under mild and environmentally friendly conditions. Key advantages of this method include short reaction times, high product yields, and efficient catalysis with minimal catalyst loading. The synthesized compounds were structurally confirmed through FT-IR, 13C NMR, and 1H NMR spectroscopy, demonstrating the efficiency and reliability of the catalytic system under green synthesis conditions.
期刊介绍：
The aim of this journal is to foster the growth of scientific research among Iranian scientists and to provide a medium which brings the fruits of their research to the attention of the world’s scientific community. The journal publishes original research findings – which may be theoretical, experimental or both - reviews, techniques, and comments spanning all subjects in the field of basic sciences, including Physics, Chemistry, Mathematics, Statistics, Biology and Earth Sciences
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