Stefania Arasi, Lars Lange, Katharina Blümchen, Nora Knappe, Katja Nemat, Randolf Brehler, Stefani Röseler, Michael Gerstlauer, Jan Hagemann, Friederike Bärhold, Ingrid Casper, Philippe Eigenmann, Alessandro Fiocchi, Ludger Klimek, Christian Vogelberg
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Severity assessment of food allergies according to DEFASE criteria in the German healthcare system (d-DEFASE)
There is currently no standardized evaluation system in Germany for defining and classifying the severity of IgE-mediated food allergies (FA). Following the development of the international classification system named DEFASE (Definition of Food Allergy Severity), this evaluation system is now also being introduced in Germany and its applicability in the German healthcare system is being tested.
An international consensus was reached on DEFASE through a two-stage process (systematic literature review followed by an e‑Delphi).
The DEFASE score is the first comprehensive classification of the severity of a FA that takes into account not only the severity of an individual reaction, but the entire scenario of the disease, including the clinical features alongside patient’s reported outcomes and economic burden. It is important that an international consensus has been reached on a scoring system for FA, which can now also be used in Germany as d‑DEFASE. The scoring system is currently tested in research projects to be introduced soon into clinical practice, targeting these models to various food allergenic sources, populations, and settings.
期刊介绍：
Allergo Journal International is the official Journal of the German Society for Applied Allergology (AeDA) and the Austrian Society for Allergology and Immunology (ÖGAI). The journal is a forum for the communication and exchange of ideas concerning the various aspects of allergy (including related fields such as clinical immunology and environmental medicine) and promotes German allergy research in an international context. The aim of Allergo Journal International is to provide state of the art information for all medical and scientific disciplines that deal with allergic, immunological and environmental diseases. Allergo Journal International publishes original articles, reviews, short communications, case reports, and letters to the editor. The articles cover topics such as allergic, immunological and environmental diseases, the latest developments in diagnosis and therapy as well as current research work concerning antigens and allergens and aspects related to occupational and environmental medicine. In addition, it publishes clinical guidelines and position papers approved by expert panels of the German, Austrian and Swiss Allergy Societies.
All submissions are reviewed in single-blind fashion by at least two reviewers.
Originally, the journal started as a German journal called Allergo Journal back in 1992. Throughout the years, English articles amounted to a considerable portion in Allergo Journal. This was one of the reasons to extract the scientific content and publish it in a separate journal. Hence, Allergo Journal International was born and now is the international continuation of the original German journal. Nowadays, all original content is published in Allergo Journal International first. Later, selected manuscripts will be translated and published in German and included in Allergo Journal.
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