{"title":"-葡聚糖的医药应用综述","authors":"Pooja Anand Mundada, Hitendra Shaligram Mahajan","doi":"10.1186/s43094-025-00835-1","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Beta-glucan (BG) is a diverse group of polysaccharides widely distributed in nature, including fungi, algae, bacteria, and cereals. Due to its unique physicochemical and biological properties, BG has gained significant attention in various fields, such as pharmaceuticals, cosmetics, nutraceuticals, and agriculture.</p><h3>Main body</h3><p>This article provides a comprehensive overview of BG’s applications and highlights their potential benefits in pharmaceuticals. BG has demonstrated significant potential as an immunomodulatory agent in the pharmaceutical field. They can stimulate the immune system, enhance the activity of macrophages, and increase the production of cytokines. This makes BG valuable in developing immunotherapeutic drugs, vaccine adjuvants, and wound-healing formulations. Additionally, BG has shown anticancer properties and has been investigated as a potential cancer prevention and treatment agent.</p><h3>Conclusion</h3><p>Overall, this overview highlights the diverse applications of BG in pharmaceuticals. Their functional and bioactive properties make them versatile ingredients in pharmaceuticals. The understanding of BG structure–function relationships and their mechanisms of action continues to expand, paving the way for future novel and innovative uses of these polysaccharides.</p></div>","PeriodicalId":577,"journal":{"name":"Future Journal of Pharmaceutical Sciences","volume":"11 1","pages":""},"PeriodicalIF":3.0000,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://fjps.springeropen.com/counter/pdf/10.1186/s43094-025-00835-1","citationCount":"0","resultStr":"{\"title\":\"Pharmaceutical application of beta-glucan: a comprehensive overview\",\"authors\":\"Pooja Anand Mundada, Hitendra Shaligram Mahajan\",\"doi\":\"10.1186/s43094-025-00835-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Beta-glucan (BG) is a diverse group of polysaccharides widely distributed in nature, including fungi, algae, bacteria, and cereals. Due to its unique physicochemical and biological properties, BG has gained significant attention in various fields, such as pharmaceuticals, cosmetics, nutraceuticals, and agriculture.</p><h3>Main body</h3><p>This article provides a comprehensive overview of BG’s applications and highlights their potential benefits in pharmaceuticals. BG has demonstrated significant potential as an immunomodulatory agent in the pharmaceutical field. They can stimulate the immune system, enhance the activity of macrophages, and increase the production of cytokines. This makes BG valuable in developing immunotherapeutic drugs, vaccine adjuvants, and wound-healing formulations. Additionally, BG has shown anticancer properties and has been investigated as a potential cancer prevention and treatment agent.</p><h3>Conclusion</h3><p>Overall, this overview highlights the diverse applications of BG in pharmaceuticals. Their functional and bioactive properties make them versatile ingredients in pharmaceuticals. The understanding of BG structure–function relationships and their mechanisms of action continues to expand, paving the way for future novel and innovative uses of these polysaccharides.</p></div>\",\"PeriodicalId\":577,\"journal\":{\"name\":\"Future Journal of Pharmaceutical Sciences\",\"volume\":\"11 1\",\"pages\":\"\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2025-06-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://fjps.springeropen.com/counter/pdf/10.1186/s43094-025-00835-1\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Future Journal of Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://link.springer.com/article/10.1186/s43094-025-00835-1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Journal of Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1186/s43094-025-00835-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Pharmaceutical application of beta-glucan: a comprehensive overview
Background
Beta-glucan (BG) is a diverse group of polysaccharides widely distributed in nature, including fungi, algae, bacteria, and cereals. Due to its unique physicochemical and biological properties, BG has gained significant attention in various fields, such as pharmaceuticals, cosmetics, nutraceuticals, and agriculture.
Main body
This article provides a comprehensive overview of BG’s applications and highlights their potential benefits in pharmaceuticals. BG has demonstrated significant potential as an immunomodulatory agent in the pharmaceutical field. They can stimulate the immune system, enhance the activity of macrophages, and increase the production of cytokines. This makes BG valuable in developing immunotherapeutic drugs, vaccine adjuvants, and wound-healing formulations. Additionally, BG has shown anticancer properties and has been investigated as a potential cancer prevention and treatment agent.
Conclusion
Overall, this overview highlights the diverse applications of BG in pharmaceuticals. Their functional and bioactive properties make them versatile ingredients in pharmaceuticals. The understanding of BG structure–function relationships and their mechanisms of action continues to expand, paving the way for future novel and innovative uses of these polysaccharides.
期刊介绍：
Future Journal of Pharmaceutical Sciences (FJPS) is the official journal of the Future University in Egypt. It is a peer-reviewed, open access journal which publishes original research articles, review articles and case studies on all aspects of pharmaceutical sciences and technologies, pharmacy practice and related clinical aspects, and pharmacy education. The journal publishes articles covering developments in drug absorption and metabolism, pharmacokinetics and dynamics, drug delivery systems, drug targeting and nano-technology. It also covers development of new systems, methods and techniques in pharmacy education and practice. The scope of the journal also extends to cover advancements in toxicology, cell and molecular biology, biomedical research, clinical and pharmaceutical microbiology, pharmaceutical biotechnology, medicinal chemistry, phytochemistry and nutraceuticals.
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