{"title":"贻贝:营养物质、生物活性肽和矿物质的宝库——它们在食品、制药和生物医学中的应用综述","authors":"Joshna Koodathil, Kiranvikas Elavarasan, Hema Munusamy, Nithish kumar Arivukkarasu, Kamesh Sendhil Murugan, Dharshini jeyasankar","doi":"10.1186/s43094-025-00840-4","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Marine ecosystems are essential for sustaining biodiversity and providing nutritional resources. Mussels are a sustainable and highly nutritious protein source with growing significance in addressing global food security. Their high protein content, bioactive compounds, and eco-friendly cultivation make them an ideal alternative to traditional protein sources. </p><h3>Main body</h3><p>Mussel proteins offer remarkable nutritional value, with an amino acid score of 107 and significant biological activities, including antioxidant, antihypertensive, and anticancer properties. Mussel-derived bioactive peptides, obtained through enzymatic hydrolysis, have shown pharmacological benefits such as anti-inflammatory, immunoregulatory, and cardiovascular health-promoting effects. Additionally, mussel shells, rich in calcium carbonate, have potential applications in food fortification, pharmaceuticals, and biomedical fields. The extraction and utilization of mussel-derived compounds for functional foods and nutraceuticals enhance their industrial relevance. By isolating these compounds from various types of mussel, various pharmaceutical researches may lead to various uses. Isolation may contain various methods but some of important methods are discussed below; even waste mussel shell also has rich nutritional values where extraction is done by double displacement and neutralization method. This calcium content can be used as calcium supplements and for various dental treatments, and mussel protein extraction is isolated by the pH-shift method. However, refining protein extraction techniques and improving consumer acceptance remain key challenges. </p><h3>Conclusion</h3><p>Mussels are an excellent source of sustainable nutrition and bioactive compounds with diverse applications in food, pharmaceutical, and biomedical industries. Their inclusion in functional foods enhances nutritional quality and health benefits. Future research should focus on refining processing techniques, expanding consumer awareness, and exploring novel applications to fully use mussel-based ingredients for a sustainable and health-conscious future. </p></div>","PeriodicalId":577,"journal":{"name":"Future Journal of Pharmaceutical Sciences","volume":"11 1","pages":""},"PeriodicalIF":3.0000,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://fjps.springeropen.com/counter/pdf/10.1186/s43094-025-00840-4","citationCount":"0","resultStr":"{\"title\":\"Mussels: a treasure trove of nutrients, bioactive peptides, and minerals-a review of their applications in food, pharmaceuticals, and biomedicine\",\"authors\":\"Joshna Koodathil, Kiranvikas Elavarasan, Hema Munusamy, Nithish kumar Arivukkarasu, Kamesh Sendhil Murugan, Dharshini jeyasankar\",\"doi\":\"10.1186/s43094-025-00840-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Marine ecosystems are essential for sustaining biodiversity and providing nutritional resources. Mussels are a sustainable and highly nutritious protein source with growing significance in addressing global food security. Their high protein content, bioactive compounds, and eco-friendly cultivation make them an ideal alternative to traditional protein sources. </p><h3>Main body</h3><p>Mussel proteins offer remarkable nutritional value, with an amino acid score of 107 and significant biological activities, including antioxidant, antihypertensive, and anticancer properties. Mussel-derived bioactive peptides, obtained through enzymatic hydrolysis, have shown pharmacological benefits such as anti-inflammatory, immunoregulatory, and cardiovascular health-promoting effects. Additionally, mussel shells, rich in calcium carbonate, have potential applications in food fortification, pharmaceuticals, and biomedical fields. The extraction and utilization of mussel-derived compounds for functional foods and nutraceuticals enhance their industrial relevance. By isolating these compounds from various types of mussel, various pharmaceutical researches may lead to various uses. Isolation may contain various methods but some of important methods are discussed below; even waste mussel shell also has rich nutritional values where extraction is done by double displacement and neutralization method. This calcium content can be used as calcium supplements and for various dental treatments, and mussel protein extraction is isolated by the pH-shift method. However, refining protein extraction techniques and improving consumer acceptance remain key challenges. </p><h3>Conclusion</h3><p>Mussels are an excellent source of sustainable nutrition and bioactive compounds with diverse applications in food, pharmaceutical, and biomedical industries. Their inclusion in functional foods enhances nutritional quality and health benefits. Future research should focus on refining processing techniques, expanding consumer awareness, and exploring novel applications to fully use mussel-based ingredients for a sustainable and health-conscious future. </p></div>\",\"PeriodicalId\":577,\"journal\":{\"name\":\"Future Journal of Pharmaceutical Sciences\",\"volume\":\"11 1\",\"pages\":\"\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2025-07-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://fjps.springeropen.com/counter/pdf/10.1186/s43094-025-00840-4\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Future Journal of Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://link.springer.com/article/10.1186/s43094-025-00840-4\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Journal of Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1186/s43094-025-00840-4","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Mussels: a treasure trove of nutrients, bioactive peptides, and minerals-a review of their applications in food, pharmaceuticals, and biomedicine
Background
Marine ecosystems are essential for sustaining biodiversity and providing nutritional resources. Mussels are a sustainable and highly nutritious protein source with growing significance in addressing global food security. Their high protein content, bioactive compounds, and eco-friendly cultivation make them an ideal alternative to traditional protein sources.
Main body
Mussel proteins offer remarkable nutritional value, with an amino acid score of 107 and significant biological activities, including antioxidant, antihypertensive, and anticancer properties. Mussel-derived bioactive peptides, obtained through enzymatic hydrolysis, have shown pharmacological benefits such as anti-inflammatory, immunoregulatory, and cardiovascular health-promoting effects. Additionally, mussel shells, rich in calcium carbonate, have potential applications in food fortification, pharmaceuticals, and biomedical fields. The extraction and utilization of mussel-derived compounds for functional foods and nutraceuticals enhance their industrial relevance. By isolating these compounds from various types of mussel, various pharmaceutical researches may lead to various uses. Isolation may contain various methods but some of important methods are discussed below; even waste mussel shell also has rich nutritional values where extraction is done by double displacement and neutralization method. This calcium content can be used as calcium supplements and for various dental treatments, and mussel protein extraction is isolated by the pH-shift method. However, refining protein extraction techniques and improving consumer acceptance remain key challenges.
Conclusion
Mussels are an excellent source of sustainable nutrition and bioactive compounds with diverse applications in food, pharmaceutical, and biomedical industries. Their inclusion in functional foods enhances nutritional quality and health benefits. Future research should focus on refining processing techniques, expanding consumer awareness, and exploring novel applications to fully use mussel-based ingredients for a sustainable and health-conscious future.
期刊介绍:
Future Journal of Pharmaceutical Sciences (FJPS) is the official journal of the Future University in Egypt. It is a peer-reviewed, open access journal which publishes original research articles, review articles and case studies on all aspects of pharmaceutical sciences and technologies, pharmacy practice and related clinical aspects, and pharmacy education. The journal publishes articles covering developments in drug absorption and metabolism, pharmacokinetics and dynamics, drug delivery systems, drug targeting and nano-technology. It also covers development of new systems, methods and techniques in pharmacy education and practice. The scope of the journal also extends to cover advancements in toxicology, cell and molecular biology, biomedical research, clinical and pharmaceutical microbiology, pharmaceutical biotechnology, medicinal chemistry, phytochemistry and nutraceuticals.