Muhammad Saood , Qasim Khalid , Wajiha Abbas , Umer Hussain , Marium Jamil , Umar Hussain , Alessandra Campobasso , Junad Khan
{"title":"不同颅面形态的下颌联合尺寸:系统回顾和荟萃分析","authors":"Muhammad Saood , Qasim Khalid , Wajiha Abbas , Umer Hussain , Marium Jamil , Umar Hussain , Alessandra Campobasso , Junad Khan","doi":"10.1016/j.ortho.2025.101065","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate and synthesize the available evidence on mandibular symphysis dimensions across different sagittal and vertical craniofacial skeletal patterns.</div></div><div><h3>Methods</h3><div>Eligibility criteria: cross sectional studies comparing mandibular symphysis dimensions among individuals with different sagittal and vertical skeletal patterns. Information sources: unrestricted literature search of six databases (PubMed, Scopus, Web of Science, LILACs, Cochrane and Google Scholar) was conducted up to April 2025 without language restriction. Risk of bias: the quality assessment of the included studies was conducted using Joanna Briggs Institute tool. Synthesis of results: random-effects meta-analyses were performed using mean differences (MDs) and 95% confidence intervals (CIs). Heterogeneity was assessed using I<sup>2</sup> and Tau<sup>2</sup> statistics. Subgroup analyses were conducted based on ethnicity, imaging modality, and risk of bias. Publication bias was evaluated.</div></div><div><h3>Results</h3><div>Included studies: twenty-three cross-sectional studies involving 3313 participants (40.35% male) were included. Synthesis of results: class III subjects showed significantly greater symphysis area (MD<!--> <!-->=<!--> <!-->2.37[1.33, 3.41]), height (MD<!--> <!-->=<!--> <!-->0.75[0.27, 1.22]), and convexity (MD<!--> <!-->=<!--> <!-->3.59[0.69, 6.49]) compared to Class I. Hyperdivergent individuals had increased symphysis height (MD<!--> <!-->=<!--> <!-->1.31[0.53, 2.1]) and reduced width (MD<!--> <!-->=<!--> <!-->–1.25[–2.37,–0.12]), while hypodivergent individuals showed reduced height (MD<!--> <!-->=<!--> <!-->–0.68[–1.34,–0.03]) and increased width (MD<!--> <!-->=<!--> <!-->1.42[0.41, 2.42]). Subgroup analyses revealed ethnicity and risk of bias as significant modifiers, particularly in Class II and vertical pattern comparisons. No significant publication bias was detected.</div></div><div><h3>Discussion</h3><div>Limitations of evidence: the inclusion of mostly retrospective studies, presence of growing individuals, inadequate control for confounders, inconsistent age and sex reporting, and limited outcome data restricted the strength and scope of the meta-analysis. Interpretation: symphysis dimensions vary by skeletal pattern, with vertical growth type showing stronger associations than sagittal class.</div></div><div><h3>Registration</h3><div>PROPSERO (CRD420251049382).</div></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"24 1","pages":"Article 101065"},"PeriodicalIF":1.9000,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mandibular symphysis dimensions among various craniofacial patterns: A systematic review and meta-analysis\",\"authors\":\"Muhammad Saood , Qasim Khalid , Wajiha Abbas , Umer Hussain , Marium Jamil , Umar Hussain , Alessandra Campobasso , Junad Khan\",\"doi\":\"10.1016/j.ortho.2025.101065\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><div>To evaluate and synthesize the available evidence on mandibular symphysis dimensions across different sagittal and vertical craniofacial skeletal patterns.</div></div><div><h3>Methods</h3><div>Eligibility criteria: cross sectional studies comparing mandibular symphysis dimensions among individuals with different sagittal and vertical skeletal patterns. Information sources: unrestricted literature search of six databases (PubMed, Scopus, Web of Science, LILACs, Cochrane and Google Scholar) was conducted up to April 2025 without language restriction. Risk of bias: the quality assessment of the included studies was conducted using Joanna Briggs Institute tool. Synthesis of results: random-effects meta-analyses were performed using mean differences (MDs) and 95% confidence intervals (CIs). Heterogeneity was assessed using I<sup>2</sup> and Tau<sup>2</sup> statistics. Subgroup analyses were conducted based on ethnicity, imaging modality, and risk of bias. Publication bias was evaluated.</div></div><div><h3>Results</h3><div>Included studies: twenty-three cross-sectional studies involving 3313 participants (40.35% male) were included. Synthesis of results: class III subjects showed significantly greater symphysis area (MD<!--> <!-->=<!--> <!-->2.37[1.33, 3.41]), height (MD<!--> <!-->=<!--> <!-->0.75[0.27, 1.22]), and convexity (MD<!--> <!-->=<!--> <!-->3.59[0.69, 6.49]) compared to Class I. Hyperdivergent individuals had increased symphysis height (MD<!--> <!-->=<!--> <!-->1.31[0.53, 2.1]) and reduced width (MD<!--> <!-->=<!--> <!-->–1.25[–2.37,–0.12]), while hypodivergent individuals showed reduced height (MD<!--> <!-->=<!--> <!-->–0.68[–1.34,–0.03]) and increased width (MD<!--> <!-->=<!--> <!-->1.42[0.41, 2.42]). Subgroup analyses revealed ethnicity and risk of bias as significant modifiers, particularly in Class II and vertical pattern comparisons. No significant publication bias was detected.</div></div><div><h3>Discussion</h3><div>Limitations of evidence: the inclusion of mostly retrospective studies, presence of growing individuals, inadequate control for confounders, inconsistent age and sex reporting, and limited outcome data restricted the strength and scope of the meta-analysis. Interpretation: symphysis dimensions vary by skeletal pattern, with vertical growth type showing stronger associations than sagittal class.</div></div><div><h3>Registration</h3><div>PROPSERO (CRD420251049382).</div></div>\",\"PeriodicalId\":45449,\"journal\":{\"name\":\"International Orthodontics\",\"volume\":\"24 1\",\"pages\":\"Article 101065\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-09-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Orthodontics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1761722725001007\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Orthodontics","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1761722725001007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Mandibular symphysis dimensions among various craniofacial patterns: A systematic review and meta-analysis
Objectives
To evaluate and synthesize the available evidence on mandibular symphysis dimensions across different sagittal and vertical craniofacial skeletal patterns.
Methods
Eligibility criteria: cross sectional studies comparing mandibular symphysis dimensions among individuals with different sagittal and vertical skeletal patterns. Information sources: unrestricted literature search of six databases (PubMed, Scopus, Web of Science, LILACs, Cochrane and Google Scholar) was conducted up to April 2025 without language restriction. Risk of bias: the quality assessment of the included studies was conducted using Joanna Briggs Institute tool. Synthesis of results: random-effects meta-analyses were performed using mean differences (MDs) and 95% confidence intervals (CIs). Heterogeneity was assessed using I2 and Tau2 statistics. Subgroup analyses were conducted based on ethnicity, imaging modality, and risk of bias. Publication bias was evaluated.
Results
Included studies: twenty-three cross-sectional studies involving 3313 participants (40.35% male) were included. Synthesis of results: class III subjects showed significantly greater symphysis area (MD = 2.37[1.33, 3.41]), height (MD = 0.75[0.27, 1.22]), and convexity (MD = 3.59[0.69, 6.49]) compared to Class I. Hyperdivergent individuals had increased symphysis height (MD = 1.31[0.53, 2.1]) and reduced width (MD = –1.25[–2.37,–0.12]), while hypodivergent individuals showed reduced height (MD = –0.68[–1.34,–0.03]) and increased width (MD = 1.42[0.41, 2.42]). Subgroup analyses revealed ethnicity and risk of bias as significant modifiers, particularly in Class II and vertical pattern comparisons. No significant publication bias was detected.
Discussion
Limitations of evidence: the inclusion of mostly retrospective studies, presence of growing individuals, inadequate control for confounders, inconsistent age and sex reporting, and limited outcome data restricted the strength and scope of the meta-analysis. Interpretation: symphysis dimensions vary by skeletal pattern, with vertical growth type showing stronger associations than sagittal class.
期刊介绍:
Une revue de référence dans le domaine de orthodontie et des disciplines frontières Your reference in dentofacial orthopedics International Orthodontics adresse aux orthodontistes, aux dentistes, aux stomatologistes, aux chirurgiens maxillo-faciaux et aux plasticiens de la face, ainsi quà leurs assistant(e)s. International Orthodontics is addressed to orthodontists, dentists, stomatologists, maxillofacial surgeons and facial plastic surgeons, as well as their assistants.