模拟细胞骨架和细胞动力学

IF 4.3 2区生物学 Q1 CELL BIOLOGY

Current Opinion in Cell Biology Pub Date : 2025-09-25 DOI:10.1016/j.ceb.2025.102584

Christoph Anton , Franziska Lautenschläger , Rhoda J. Hawkins

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引用次数: 0

摘要

在这里，我们概述了最近的理论和实验工作，模拟的力学和动力学的细胞骨架。细胞骨架是一种多组分、复杂的活性物质，对细胞力学和动力学至关重要。我们关注这种材料的主要成分之一，即肌动蛋白丝。我们讨论这些细丝及其与细胞骨架内其他蛋白质的相互作用。为了充分了解细胞骨架，重要的是要考虑结石，硅，体外，体内和原位的理论和实验工作。我们回顾了目前的知识状况，并期待在尚未理解的方面开展进一步的工作。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Modeling cytoskeletal and cell dynamics

Here we give an overview of recent theoretical and experimental work on modeling the mechanics and dynamics of the cytoskeleton. The cytoskeleton is a multicomponent, complex and active material that is essential to cell mechanics and dynamics. We focus on one of the main components of this material, namely actin filaments. We discuss these filaments and their interactions with other proteins within the cytoskeleton. To fully understand the cytoskeleton, it is important to consider both theoretical and experimental work in calculo, in silico, in vitro, in vivo, and in situ. We review the current state of knowledge and look forward to further work to come on aspects not yet understood.

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来源期刊

Current Opinion in Cell Biology 生物-细胞生物学

CiteScore

14.60

自引率

1.30%

发文量

审稿时长

93 days

期刊介绍： Current Opinion in Cell Biology (COCEBI) is a highly respected journal that specializes in publishing authoritative, comprehensive, and systematic reviews in the field of cell biology. The journal's primary aim is to provide a clear and readable synthesis of the latest advances in cell biology, helping specialists stay current with the rapidly evolving field. Expert authors contribute to the journal by annotating and highlighting the most significant papers from the extensive body of research published annually, offering valuable insights and saving time for readers by distilling key findings. COCEBI is part of the Current Opinion and Research (CO+RE) suite of journals, which leverages the legacy of editorial excellence, high impact, and global reach to ensure that the journal is a widely read resource integral to scientists' workflow. It is published by Elsevier, a publisher known for its commitment to excellence in scientific publishing and the communication of reproducible biomedical research aimed at improving human health. The journal's content is designed to be an invaluable resource for a diverse audience, including researchers, lecturers, teachers, professionals, policymakers, and students.