Lingual-masticatory myorhythmia and palatal tremor as a presentation of anti-IgLON5 disease

Anti-IgLON5 disease is a progressive neurological disorder at the intersection of autoimmunity and neurodegeneration, with an increasingly recognized and heterogeneous clinical spectrum. While movement disorders such as chorea and parkinsonism have been reported, myorhythmia remains a rare manifestation. We describe a case of anti-IgLON5 disease presenting with characteristic lingual-masticatory myorhythmia and palatal tremor, which responded favorably to immunotherapy. This case underscores the diagnostic value of these uncommon movement phenomena and highlights their potential reversibility with timely immunosuppressive treatment.