以烯基硅烷为乙烯源钯催化羰基化四组分合成β-全氟烷基酰胺

IF 6.5 1区化学 Q2 CHEMISTRY, PHYSICAL

Journal of Catalysis Pub Date : 2025-09-26 DOI:10.1016/j.jcat.2025.116450

Yong-Wang Huo, Xiao-Feng Wu

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引用次数: 0

摘要

在传统的乙烯气改造中，除了需要乙烯气瓶和相关的安全问题外，还产生了大量的乙烯释放和浪费。在此，我们开发了钯催化的四组分全氟烷基化/氨基羰基化反应，以高效合成β-全氟烷基酰胺。这种转化采用低毒性和高稳定性的烯基硅烷作为乙烯替代物，可以控制乙烯的用量，在相对温和的条件下以中等到良好的产量提供各种β-全氟烷基酰胺。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Palladium-catalyzed carbonylative four-component synthesis of β-perfluoroalkyl amides with alkenylsilanes as the ethylene source

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Palladium-catalyzed carbonylative four-component synthesis of β-perfluoroalkyl amides with alkenylsilanes as the ethylene source

In the traditional transformations with ethylene gas, besides the needing of ethylene cylinder and related safety issues, significant amount of ethylene was released and wasted. Herein, we developed a palladium-catalyzed four-component perfluoroalkylation/aminocarbonylation reaction for the efficient synthesis of β-perfluoroalkyl amides. This transformation employs low-toxicity and highly stable alkenylsilanes as an ethylene surrogate which can make the dosing of ethylene controllable, delivering diverse β-perfluoroalkyl amides in moderate to good yields under relatively mild conditions.

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来源期刊

Journal of Catalysis 工程技术-工程：化工

CiteScore

12.30

自引率

5.50%

发文量

447

审稿时长

31 days

期刊介绍： The Journal of Catalysis publishes scholarly articles on both heterogeneous and homogeneous catalysis, covering a wide range of chemical transformations. These include various types of catalysis, such as those mediated by photons, plasmons, and electrons. The focus of the studies is to understand the relationship between catalytic function and the underlying chemical properties of surfaces and metal complexes. The articles in the journal offer innovative concepts and explore the synthesis and kinetics of inorganic solids and homogeneous complexes. Furthermore, they discuss spectroscopic techniques for characterizing catalysts, investigate the interaction of probes and reacting species with catalysts, and employ theoretical methods. The research presented in the journal should have direct relevance to the field of catalytic processes, addressing either fundamental aspects or applications of catalysis.