{"title":"口腔鳞状细胞癌术前淋巴结状态预测：定量双能CT参数的价值。","authors":"Fengqiong Huang, Xiaohua Ban, Yusong Jiang, Guoxiong Lu, Fang Zhang","doi":"10.1016/j.oooo.2025.08.005","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this study was to explore whether parameters of dual-energy computed tomography (DECT) could help evaluate the status of cervical lymph nodes (LNs) in patients with oral squamous cell carcinoma (OSCC).</p><p><strong>Study design: </strong>Pathological and DECT parameters of patients with OSCC who underwent cervical lymph node dissection from December 2021 to December 2022 were collected. Quantitative DECT parameters of the primary lesions, including the slope of the spectral Hounsfield unit curve (λ<sub>HU</sub>), iodine concentration (IC), electron density (Rho), normalized iodine concentration (NIC), and effective atomic number (Z<sub>eff</sub>), were measured between patients with different lymph node status (the presence of LN metastasis, lymph node ratio [LNR], and lymph node burden [LNB]). The receiver operating characteristic curves and logistic regression analysis were used to evaluate the diagnostic performance and the independent parameters, respectively.</p><p><strong>Results: </strong>The independent predictor for the detection of LN metastasis was λ<sub>HU</sub> in venous phase, with an area under the curve (AUC) of 0.812. The mean precontrast Z<sub>eff</sub> was higher in the high metastatic LNB group than the low metastatic LNB group. The precontrast Z<sub>eff</sub> was the independent predictor of high LNR with an AUC of 0.726.</p><p><strong>Conclusions: </strong>DECT quantitative parameters of the primary lesions can facilitate the evaluation of cervical LN status.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Preoperative Prediction of Lymph Node Status in Oral Squamous Cell Carcinoma: Value of Quantitative Dual-Energy CT Parameters.\",\"authors\":\"Fengqiong Huang, Xiaohua Ban, Yusong Jiang, Guoxiong Lu, Fang Zhang\",\"doi\":\"10.1016/j.oooo.2025.08.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>The objective of this study was to explore whether parameters of dual-energy computed tomography (DECT) could help evaluate the status of cervical lymph nodes (LNs) in patients with oral squamous cell carcinoma (OSCC).</p><p><strong>Study design: </strong>Pathological and DECT parameters of patients with OSCC who underwent cervical lymph node dissection from December 2021 to December 2022 were collected. Quantitative DECT parameters of the primary lesions, including the slope of the spectral Hounsfield unit curve (λ<sub>HU</sub>), iodine concentration (IC), electron density (Rho), normalized iodine concentration (NIC), and effective atomic number (Z<sub>eff</sub>), were measured between patients with different lymph node status (the presence of LN metastasis, lymph node ratio [LNR], and lymph node burden [LNB]). The receiver operating characteristic curves and logistic regression analysis were used to evaluate the diagnostic performance and the independent parameters, respectively.</p><p><strong>Results: </strong>The independent predictor for the detection of LN metastasis was λ<sub>HU</sub> in venous phase, with an area under the curve (AUC) of 0.812. The mean precontrast Z<sub>eff</sub> was higher in the high metastatic LNB group than the low metastatic LNB group. The precontrast Z<sub>eff</sub> was the independent predictor of high LNR with an AUC of 0.726.</p><p><strong>Conclusions: </strong>DECT quantitative parameters of the primary lesions can facilitate the evaluation of cervical LN status.</p>\",\"PeriodicalId\":49010,\"journal\":{\"name\":\"Oral Surgery Oral Medicine Oral Pathology Oral Radiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-08-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oral Surgery Oral Medicine Oral Pathology Oral Radiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.oooo.2025.08.005\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.oooo.2025.08.005","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Preoperative Prediction of Lymph Node Status in Oral Squamous Cell Carcinoma: Value of Quantitative Dual-Energy CT Parameters.
Objectives: The objective of this study was to explore whether parameters of dual-energy computed tomography (DECT) could help evaluate the status of cervical lymph nodes (LNs) in patients with oral squamous cell carcinoma (OSCC).
Study design: Pathological and DECT parameters of patients with OSCC who underwent cervical lymph node dissection from December 2021 to December 2022 were collected. Quantitative DECT parameters of the primary lesions, including the slope of the spectral Hounsfield unit curve (λHU), iodine concentration (IC), electron density (Rho), normalized iodine concentration (NIC), and effective atomic number (Zeff), were measured between patients with different lymph node status (the presence of LN metastasis, lymph node ratio [LNR], and lymph node burden [LNB]). The receiver operating characteristic curves and logistic regression analysis were used to evaluate the diagnostic performance and the independent parameters, respectively.
Results: The independent predictor for the detection of LN metastasis was λHU in venous phase, with an area under the curve (AUC) of 0.812. The mean precontrast Zeff was higher in the high metastatic LNB group than the low metastatic LNB group. The precontrast Zeff was the independent predictor of high LNR with an AUC of 0.726.
Conclusions: DECT quantitative parameters of the primary lesions can facilitate the evaluation of cervical LN status.
期刊介绍：
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
