Gabriel Rodrigues Aguiar, Alberto Souza de Sá Filho, Marcelo Couto Jorge Rodrigues, Eduardo Macedo Penna, Vicente Aprigliano, Claudio Andre Barbosa de Lira, Augusto Cezar Rodrigues Rocha, Gabriela Souza de Vasconcelos, Else Saliés Fonseca, José Carlos Pontes Corrêa, Matias Noll, Gustavo De Conti Teixeira Costa
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引用次数: 0
摘要
背景：精神疲劳（MF）是一种损害身体和认知表现的心理生物学状态，特别是在耐力和阻力任务中。经颅直流电刺激（tDCS）已成为一种有前途的无创神经调节技术，以减轻MF和增加运动能力。然而，由于刺激参数、疲劳诱导方案和结果评估的方法异质性，证据仍然不一致。本研究旨在系统回顾随机对照试验（rct），这些试验调查了在包括运动员在内的健康、身体活跃的成年人中，主动和虚假tDCS对降低MF和改善身体表现（如疲劳时间和肌肉耐力）的影响。方法：该方案遵循PRISMA-P指南，并在PROSPERO注册（CRD4202541050229）。符合条件的研究将包括rct（平行或交叉），比较活动tDCS（任何经过验证的方案）与假刺激在≥18岁无神经、精神或心血管疾病的成年人中的作用。检索将在PubMed， Embase, Scopus, Web of Science, SPORTDiscus， PsycINFO和ClinicalTrials.gov中进行。主要结果是耗尽的时间和重复失败的次数；次要结局包括MF评分。两名独立审稿人将选择研究，提取数据，并使用Cochrane RoB 2.0评估偏倚风险。在可能的情况下进行荟萃分析，适当时进行亚组、敏感性和元回归分析。讨论：这篇综述将综合现有的关于tDCS对健康成人MF和身体机能的影响的证据。研究结果旨在为未来研究的设计提供信息，并支持体育和运动科学中tDCS协议的标准化。系统评价注册：PROSPERO CRD420251050229。
Effects of transcranial direct current stimulation on mental fatigue reduction and physical performance improvement in healthy adults: a systematic review protocol.
Background: Mental fatigue (MF) is a psychobiological state that impairs physical and cognitive performance, particularly in endurance and resistance tasks. Transcranial direct current stimulation (tDCS) has emerged as a promising noninvasive neuromodulation technique to mitigate MF and increase exercise capacity. However, evidence remains inconsistent due to methodological heterogeneity in stimulation parameters, fatigue induction protocols, and outcome assessments. This research aims to systematically review randomized controlled trials (RCTs) investigating the effects of active versus sham tDCS on reducing MF and improving physical performance, such as time to exhaustion and muscular endurance, in healthy, physically active adults, including athletes.
Methods: This protocol follows the PRISMA-P guidelines and is registered with PROSPERO (CRD4202541050229). Eligible studies will include RCTs (parallel or crossover) comparing active tDCS (any validated protocol) with sham stimulation in adults ≥ 18 years of age without neurological, psychiatric, or cardiovascular conditions. Searches will be conducted in PubMed, Embase, Scopus, Web of Science, SPORTDiscus, PsycINFO, and ClinicalTrials.gov. Primary outcomes are time to exhaustion and number of repetitions to failure; secondary outcomes include MF scores. Two independent reviewers will select studies, extract data, and assess risk of bias using Cochrane RoB 2.0. Metaanalyses will be performed where possible, with subgroup, sensitivity, and metaregression analyses as appropriate.
Discussion: This review will synthesize the available evidence on the efficacy of tDCS on MF and physical performance in healthy adults. The results aim to inform the design of future research and support the standardization of tDCS protocols in sport and exercise science.
期刊介绍：
Systematic Reviews encompasses all aspects of the design, conduct and reporting of systematic reviews. The journal publishes high quality systematic review products including systematic review protocols, systematic reviews related to a very broad definition of health, rapid reviews, updates of already completed systematic reviews, and methods research related to the science of systematic reviews, such as decision modelling. At this time Systematic Reviews does not accept reviews of in vitro studies. The journal also aims to ensure that the results of all well-conducted systematic reviews are published, regardless of their outcome.
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